Chronic Prostatitis: Symptoms, Diagnosis, and Management - Urology

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Chronic prostatitis


Two years ago, I sought medical attention for urethritis, which has recurred intermittently.
At the beginning of last year, I was diagnosed with overactive bladder, experiencing frequent urination both day and night, but without pain.
Towards the end of last year, I began to experience pain that starts at the urethral opening and glans when I have the urge to urinate, accompanied by persistent urinary frequency.
If the pain lasts too long, it can radiate to the base of the penis and perineum, but urination provides some relief.
The most significant impact is that my sleep is disturbed at night due to pain, requiring me to urinate to continue sleeping, with episodes lasting up to 2-3 hours, and sometimes occurring every 0.5-1 hour.

I have undergone a digital rectal exam, abdominal ultrasound (no stones), rectal ultrasound (prostate not enlarged), multiple urinalyses, prostate fluid, and semen tests, all showing no signs of inflammation.
I also had tests for specific pathogens (such as Chlamydia) that showed no bacterial infection.
I have taken various antibiotics, including broad-spectrum ones for over six months, with no significant improvement.
An abdominal CT scan showed mild appendicitis, but everything else was normal, and the doctor indicated there was no major issue, diagnosing me with chronic prostatitis or interstitial cystitis.
Since the beginning of this year, I have tried various pain medications, most of which have had little effect, and some have increased urinary difficulty.
It wasn't until my doctor prescribed Minirin that I experienced some relief from symptoms (pain and urgency), but its effects are temporary.
Currently, I take it three times a day and have regular follow-ups to monitor sodium levels.
However, several urologists are unclear about the efficacy of Minirin for my condition.
I have also undergone several physical therapies, including low-energy shockwave therapy, CES from psychosomatic medicine, and sympathetic nerve treatment, all with minimal effect.
Currently, I have adjusted my diet to exclude alcohol and caffeine, opting for a light diet, and I have supplemented with various nutrients such as pumpkin seeds, cod liver oil, vitamins, cranberry, rye pollen, and zinc.
Due to chronic pain, my exercise is limited to stretching, walking, or slow swimming.

I would like to ask the doctor:
1.
Given the above situation, could this be chronic prostatitis?
2.
Are there any other recommended pain relief methods or therapies?

Jimmy, 40~49 year old female. Ask Date: 2022/08/17

Dr. Du Shixi reply Urology


Hello: This information is for reference only and cannot replace a physician's examination.
Regarding the examination and tests: 1) Chronic prostatitis is a possibility.
2) This condition requires attention to lifestyle and dietary habits, as well as regular exercise, for long-term management.
Treatments generally only alleviate symptoms.
Wishing you good health.

Reply Date: 2022/08/17

More Info


Chronic prostatitis, particularly chronic pelvic pain syndrome (CPPS), can be a challenging condition to manage, especially when symptoms persist despite various treatments. Based on your detailed history, it appears that you have been experiencing a complex interplay of urinary symptoms, pain, and discomfort that has not responded well to standard treatments. Let's address your questions and provide some insights into your situation.

1. Is this chronic prostatitis?
Given your symptoms, including recurrent urinary urgency, pain during urination, and discomfort that radiates to the perineum and penis, it is plausible that you are experiencing chronic prostatitis, specifically CPPS. This condition can be categorized into inflammatory and non-inflammatory types, and it often presents with pelvic pain without evidence of urinary tract infection or inflammation in prostate secretions. Your history of negative cultures and tests for bacterial infections supports the possibility of non-bacterial prostatitis or interstitial cystitis, which can mimic prostatitis symptoms.

2. Are there other pain management strategies or therapies?
Managing chronic pelvic pain can be multifaceted. Here are several approaches that may help alleviate your symptoms:
- Physical Therapy: Pelvic floor physical therapy can be beneficial for individuals with chronic pelvic pain. A specialized therapist can help address muscle tension and dysfunction in the pelvic region, which may contribute to your symptoms.

- Pain Management Techniques: Consider exploring alternative pain management strategies such as acupuncture, biofeedback, or cognitive-behavioral therapy. These approaches can help manage pain perception and improve coping mechanisms.

- Medications: While you have tried various medications, it may be worth discussing with your physician the potential use of medications such as alpha-blockers, which can help relax the bladder neck and prostate, potentially easing urinary symptoms. Additionally, low-dose antidepressants (like amitriptyline) have been shown to help with chronic pain management.

- Dietary Adjustments: You mentioned already making dietary changes, which is excellent. Continuing to avoid irritants such as caffeine, alcohol, and spicy foods can help reduce bladder irritation. Some patients find relief with a diet rich in anti-inflammatory foods.

- Hydration: Ensure you are adequately hydrated, as concentrated urine can irritate the bladder and exacerbate symptoms.

- Regular Exercise: While chronic pain may limit your activity, gentle exercises such as walking, swimming, or yoga can improve overall well-being and may help alleviate some discomfort.

- Mind-Body Techniques: Practices such as mindfulness meditation, yoga, and relaxation techniques can help manage stress and may reduce the perception of pain.

- Follow-Up with Specialists: If your symptoms persist, consider seeking a second opinion from a urologist who specializes in chronic pelvic pain or a pain management specialist. They may offer additional insights or treatment options that have not yet been explored.

In conclusion, chronic prostatitis and CPPS can significantly impact quality of life, and finding the right combination of therapies may take time. It is essential to maintain open communication with your healthcare providers about your symptoms and treatment responses. Regular follow-ups and adjustments to your management plan will be crucial in navigating this condition. Remember, you are not alone in this journey, and there are various resources and support systems available to help you cope with chronic pelvic pain.

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