Medication Side Effects: Anxiety Drugs and Urination Issues - Psychiatry

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Drug side effects


I have been taking 20 mg of Sertraline and 1 mg of Diazepam for anxiety and autonomic nervous system dysregulation for four months.
Since mid-August, my doctor added 10 mg of Bupropion.
However, starting from August 19, I have been experiencing slower urination and decreased urine volume daily, although the color is normal.
In addition to psychiatric medications, I am also taking topical Tretinoin prescribed by a dermatologist.
I would like to know if there are any contraindications between these medications and whether my urination issues could be related to the side effects of the psychiatric medications.
Thank you!

Niming, 40~49 year old female. Ask Date: 2022/09/01

Dr. Wu Enliang reply Psychiatry


It is indeed rare for buspirone to cause urinary difficulties.
It is recommended to drink plenty of water and continue to monitor the situation.
If the issue persists and becomes intolerable, consider discontinuing the medication and discuss it with your doctor during your next visit.
Dr.
Wu Enliang.

Reply Date: 2022/09/01

More Info


When it comes to managing anxiety and the medications associated with it, understanding the potential side effects is crucial, especially when it comes to urinary issues. You mentioned that you have been taking Buspirone (安保抗憂錠) and Lorazepam (安定文) for anxiety, and recently your doctor added a dose of 10mg of another medication, likely Buspirone, which has led to changes in your urination patterns.
Firstly, it's important to recognize that medications used to treat anxiety, such as Buspirone and Lorazepam, can indeed have side effects that may affect urination. While urinary retention or changes in urination frequency are not the most common side effects, they can occur, particularly with medications that have anticholinergic properties or those that affect the central nervous system.
Buspirone is primarily used to treat anxiety and is generally well-tolerated, but it can cause side effects such as dizziness, nausea, and in rare cases, urinary issues. Lorazepam, a benzodiazepine, can also lead to sedation and may affect muscle control, which could indirectly influence urination.
The combination of these medications, especially if they are taken together, may amplify certain side effects. For instance, both medications can cause sedation, which might lead to decreased awareness of bodily functions, including the urge to urinate. Additionally, if you are experiencing anxiety, it can also affect your body's autonomic responses, including bladder control.

Regarding the topical medication you mentioned, such as A acid (likely referring to a retinoid used for skin conditions), it is generally not known to interact with anxiety medications in a way that would affect urination. However, it’s always wise to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements, to ensure there are no potential interactions.

If you are experiencing a noticeable change in urination, such as decreased frequency or difficulty urinating, it is essential to discuss this with your doctor. They may want to evaluate whether the changes are due to the medications or if there might be another underlying issue. It’s crucial not to stop or adjust your medication without consulting your healthcare provider, as this could lead to withdrawal symptoms or a resurgence of anxiety.

In summary, while it is possible that your anxiety medications could be contributing to your urinary issues, it is essential to have a thorough discussion with your healthcare provider. They can assess your symptoms, review your medication regimen, and determine the best course of action, which may include adjusting dosages or switching medications. Always prioritize open communication with your healthcare team to ensure safe and effective treatment for your anxiety and any associated side effects.

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