Recurrence of Colon Cancer: Treatment Options and Considerations - Gastroenterology and Hepatology

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Colorectal cancer recurrence


After the family member underwent tumor resection for colorectal cancer and completed a full round of chemotherapy with health insurance medications, the doctor recommended returning to first-line treatment.
However, the CT report indicates: "Growing of soft tissue lesion at left paracolic gutter, consistent with seeding tumor.
Impression: suggest left paracolic gutter seeding tumor." Does this mean the tumor has recurred at the surgical site? Shouldn't there be an urgent need for another surgery? Or can this be treated like a polyp removal? Why is the doctor advising the family member to continue chemotherapy first? Is it because of their advanced age (in their seventies) that the doctor prefers not to operate again?

Xiao Wu, 70~79 year old female. Ask Date: 2022/09/07

Dr. Cai Jinji reply Gastroenterology and Hepatology


Hello Mr.
Hsiao Wu: Due to the uncertainty regarding your family's situation (which may be quite serious), it is recommended to discuss directly with your family member's physician for clearer guidance.
Director Cai Jin-ji, Department of Hepatobiliary and Gastroenterology, Nantou Hospital.

Reply Date: 2022/09/07

More Info


Understanding the recurrence of colon cancer and the subsequent treatment options can be quite complex, especially when dealing with a loved one’s health. In the case you presented, it appears that after the initial surgical removal of a colon tumor and a full round of chemotherapy, a new lesion has developed in the left paracolic gutter, which is concerning for tumor recurrence or "seeding." This situation raises several important questions regarding the best course of action.

First, it’s essential to understand what "seeding" means in this context. Tumor seeding refers to the process where cancer cells spread to nearby tissues or organs, often occurring after surgical procedures. The presence of a growing soft tissue lesion in the left paracolic gutter suggests that cancer cells may have spread from the original tumor site. This is a critical point that needs to be addressed by the medical team.

In terms of treatment options, the decision to pursue further surgery versus continuing with chemotherapy depends on several factors, including the patient's overall health, the extent of the disease, and the potential benefits versus risks of each treatment modality. Given that the patient is in their seventies, the medical team may be weighing the risks of surgery against the potential benefits. Surgery can be more taxing on older patients, and if the cancer is not localized or if there are concerns about the patient's ability to recover, the oncologist may recommend chemotherapy as a less invasive option.

Chemotherapy, particularly in cases of recurrent cancer, is often used to control the disease and manage symptoms rather than to achieve a cure. The rationale behind continuing chemotherapy in this scenario could be to shrink the tumor or slow its growth, allowing for a better assessment of the situation before considering any surgical intervention. This approach is not uncommon, especially when the cancer is not presenting as a straightforward case for surgical resection.

The question of whether the lesion can be treated similarly to a polyp removal is also pertinent. Polyps are typically benign and can be removed with minimal risk, whereas a recurrent tumor is malignant and may require a more aggressive treatment approach. The surgical team would need to evaluate the lesion's characteristics, including its size, location, and involvement with surrounding tissues, to determine if it can be safely removed.

Regarding the concern about the patient's age and the decision to avoid surgery, it is crucial to have an open dialogue with the healthcare team. Family members should feel empowered to ask questions about the reasoning behind treatment decisions, the potential risks and benefits of surgery versus chemotherapy, and the overall prognosis. It may also be beneficial to seek a second opinion from another oncologist or surgical specialist to explore all available options.

In summary, the recurrence of colon cancer presents a challenging situation that requires careful consideration of treatment options. The decision to continue chemotherapy rather than proceed with immediate surgery may be based on the patient's overall health, the characteristics of the tumor, and the potential risks associated with surgery. Engaging in thorough discussions with the healthcare team and considering all available options, including the possibility of a second opinion, is essential for making informed decisions about the patient's care.

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