Myocardial Perfusion and Echocardiogram Reports for Heart Health - Cardiology

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Cardiac ultrasound and myocardial perfusion imaging?


Dear Dr.
Tsai,
My father is 72 years old and weighs 47 kg.
Below are the reports for his myocardial perfusion and echocardiogram.
He underwent a coronary stenting procedure on July 18, 2022, due to an acute myocardial infarction at Cheng Kung University Hospital (one stent placed in the right coronary artery).
At that time, the physician indicated that there was blockage in the left circumflex artery and left anterior descending artery, and that a second stent placement would need to consider a creatinine level below 2.0 (current lab value is 2.29).
It is anticipated that three stents will be needed.
Currently, protein intake is controlled at 0.6, and he is in stage 4 chronic kidney disease with a glomerular filtration rate of 28.
I would like to consult regarding the contents of these two reports and whether there is an urgent need for surgery, as well as any precautions that should be taken.
Thank you for your explanation; I am very grateful.
Myocardial Perfusion Report
NUCLEAR MEDICINE STUDY: Thallium-201 myocardial perfusion imaging (MPI) with dipyridamole and resting.
RADIOPHARMACEUTICAL: Intravenous 2.0 mCi Tl-201 (Thallium-201).
Reason for MPI: Diagnosis of coronary artery disease (CAD).
Symptoms/signs: Dyspnea on exertion (DOE) for years.
Risk factors: Hypertension, diabetes mellitus, dyslipidemia, chronic kidney disease, male sex, and advanced age.
Previous cardiac examinations: Cardiac echocardiogram (09/14/2022) showed normal left ventricular (LV) systolic function.
Previous intervention: None.
SCINTIGRAPHIC FINDINGS: Tl-201 SPECT was performed after a standardized dipyridamole stress protocol (dipyridamole: 0.56 mg/kg continuous IV push over 4 minutes; and aminophylline 83 mg IV infusion as needed for relief of adverse reactions) and resting state.
* Baseline ECG showed Q waves and T-wave inversions (TWI) in inferior leads.
No dynamic ST-T changes were noted during dipyridamole infusion.
* No discomfort was reported during stress.
* The initial and 4-hour delayed images showed (1) moderate reversible perfusion defect in the lateral wall; (2) the lung-heart ratio was within normal limits (stress/rest = 0.31/0.42).
Echocardiogram Report
Age: 71 Years
------------------------------------------------------------------------------+
Conclusions:
- Concentric left ventricular hypertrophy.
- The LV systolic function is normal.
- The transmitral spectral Doppler flow pattern suggests impaired LV relaxation.
- There are regional wall motion abnormalities as specified.
- Moderate tricuspid regurgitation.
- Low probability of pulmonary hypertension.
- Mild to moderate aortic regurgitation.
- Moderate mitral regurgitation.
M Mode / 2D Measurements & Calculations:
- IVSd: 1.29 cm
- LVIDd: 4.3 cm
- IVS/LVPW: 0.92
- EDV (Teich): 77.3 ml
- LA/Ao: 1.11
- LV mass (C): 214.9 grams
- LVIDs: 3.1 cm
- FS: 26.1%
- ESV (Teich): 31.3 ml
- SV (Teich): 46.0 ml
- LVPWd: 1.40 cm
- EDV (Teich): 81.2 ml
- EF (Teich): 59.6%
- RWT: 0.66
- ESV (Teich): 39.4 ml
- EF (Teich): 51.5%
- Aortic root diameter: 3.0 cm
- ACS: 1.47 cm
- LA dimension: 3.4 cm
Doppler Measurements & Calculations:
- MV E max velocity: 43.2 cm/sec
- TR max pressure gradient: 27.9 mmHg
- MV deceleration time: 0.20 sec
- Ao V2 max: 148.7 cm/sec
- MV A max velocity: 101.2 cm/sec
- E/Med E': 14.2
- Ao max pressure gradient: 8.8 mmHg
- MV E/A: 0.43
- Lat E' velocity: 5.5 cm/sec
- E/Lat E': 7.8
------------------------------------------------------------------------------+
WMSI = 1.06 % Normal = 94%
------------------------------------------------------------------------------+
Left Ventricle:
- Concentric left ventricular hypertrophy.
The LV systolic function is normal.
The transmitral spectral Doppler flow pattern suggests impaired LV relaxation.
There are regional wall motion abnormalities as specified.
Left Atrium:
- The left atrial size is normal.
Right Heart:
- The right ventricle is normal in size and function.
Normal right atrial size.
Moderate tricuspid regurgitation.
Low probability of pulmonary hypertension.
Aortic Valve:
- Fibrocalcific degeneration with satisfactory opening.
Mild to moderate aortic regurgitation.
Mitral Valve:
- Myxomatous.
Moderate mitral regurgitation.
Thank you very much.

Wang Tongyuan, 40~49 year old female. Ask Date: 2022/09/15

Dr. Cai Guiqin reply Cardiology


I recommend that you discuss the above situation further with your attending physician, focusing on symptomatic treatment or determining if further examinations are necessary.
Thank you, and wishing you good health!

Reply Date: 2022/09/15

More Info


Understanding myocardial perfusion and echocardiogram reports is crucial for assessing heart health, especially in patients with a history of cardiovascular issues. In your father's case, the reports indicate several important findings that warrant careful consideration.


Myocardial Perfusion Imaging (MPI) Report
1. Reversible Perfusion Defect: The MPI report indicates a moderate reversible perfusion defect in the lateral wall of the heart. This suggests that there may be areas of the heart muscle that are not receiving adequate blood flow during stress but can recover when the heart is at rest. This is often indicative of coronary artery disease (CAD), where blockages in the coronary arteries limit blood flow.

2. Risk Factors: Your father has several risk factors for CAD, including hypertension, diabetes, dyslipidemia, chronic kidney disease (CKD), male sex, and advanced age. These factors compound the risk of further cardiac events.

3. ECG Findings: The baseline ECG showed Q waves and T-wave inversions in the inferior leads, which can indicate previous myocardial infarction or ischemia. However, there were no dynamic ST-T changes during the stress test, which is a positive sign.

4. Heart-Lung Ratio: The lung-heart ratio being within normal limits suggests that there is no significant heart failure or pulmonary congestion at the time of the test.


Echocardiogram Report
1. Concentric Left Ventricular Hypertrophy: This finding indicates that the walls of the left ventricle are thickened, which can occur due to high blood pressure or other conditions that increase the workload on the heart. While the left ventricular (LV) systolic function is reported as normal, the presence of hypertrophy can lead to diastolic dysfunction over time.

2. Impaired LV Relaxation: The Doppler flow pattern suggests impaired relaxation of the left ventricle, which is often seen in patients with hypertension or heart failure. This can lead to symptoms of heart failure, such as shortness of breath.

3. Regional Wall Motion Abnormalities: These abnormalities can indicate areas of the heart that are not contracting effectively, often due to ischemia or previous infarction.

4. Valvular Issues: The report notes moderate mitral regurgitation and moderate tricuspid regurgitation, which can contribute to heart failure symptoms. Mild to moderate aortic regurgitation is also noted, which may require monitoring.

5. Right Heart Function: The right ventricle appears normal in size and function, which is a positive finding.


Urgency for Surgical Intervention
Given your father's history of acute myocardial infarction and the current findings, particularly the reversible perfusion defect and the presence of significant risk factors, it is essential to discuss the need for further intervention with his cardiologist. The elevated creatinine level (2.29) indicates impaired kidney function, which complicates the decision for additional stenting, as renal function is a critical factor in determining the safety and efficacy of such procedures.


Recommendations
1. Consultation with Cardiologist: It is crucial to have a detailed discussion with your father's cardiologist regarding the findings of both the MPI and echocardiogram. The cardiologist can provide insights into the urgency of further interventions, considering the balance between cardiac risk and renal function.

2. Monitoring and Management: Close monitoring of heart function and renal status is essential. Adjustments in medications, lifestyle changes, and possibly interventions to manage hypertension and diabetes will be important.

3. Lifestyle Modifications: Encourage your father to adopt heart-healthy lifestyle changes, including a balanced diet, regular physical activity (as tolerated), smoking cessation, and weight management.

4. Regular Follow-ups: Regular follow-up appointments will be necessary to monitor his heart and kidney function, as well as to reassess the need for further interventions.

In conclusion, while the reports indicate some concerning findings, they also provide a pathway for managing your father's heart health. Close collaboration with his healthcare team will be vital in navigating his treatment options and ensuring the best possible outcomes.

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