the Risk of Severe COVID-19 After Initial Mild Symptoms - Internal Medicine

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If diagnosed with COVID-19 and symptoms are becoming milder, is there a significant chance of suddenly progressing to moderate or severe symptoms?


Hello Doctor: After being diagnosed with COVID-19, I saw a doctor and received medication (it seems like the medication is mostly for cold symptoms).
I've been taking it for three days, and my symptoms have progressed from initial fever, cough, and fatigue to just a slight dry cough now.
Could you please tell me the likelihood of suddenly developing moderate to severe symptoms? (I just want to understand how likely it is to help ease my mind; I know that no one in the medical field can make absolute statements.) Thank you, Doctor.

Hao, 20~29 year old female. Ask Date: 2022/10/05

Dr. Hong Yuanbin reply Internal Medicine


Hello, if you have previously been diagnosed, your body will still have some antibodies; however, these antibodies will gradually decrease over time.
Therefore, if there is a long interval since the last infection and your immune system is not functioning well, it is indeed possible to suddenly develop severe symptoms.
Thank you for your question.

Reply Date: 2022/10/05

More Info


Understanding the risk of developing severe COVID-19 after initially experiencing mild symptoms is a crucial concern for many individuals. Based on the information provided and current medical understanding, I will address your question comprehensively.

Firstly, it is important to acknowledge that COVID-19 can present a wide range of symptoms, from mild to severe. The progression from mild symptoms to severe illness is not entirely predictable and can vary significantly from person to person. Generally, individuals who start with mild symptoms, such as fever, cough, and fatigue, may experience a decrease in symptoms over time, as you have noted. However, there is still a possibility that some individuals can experience a sudden deterioration in their condition.

Research indicates that certain factors can influence the likelihood of developing severe COVID-19 after an initial mild presentation. These factors include age, underlying health conditions (such as obesity, diabetes, or cardiovascular disease), and the presence of specific symptoms at the onset of the illness. For instance, individuals with pre-existing health issues are at a higher risk of experiencing severe outcomes, even if their initial symptoms were mild.

In your case, since you have been experiencing a reduction in symptoms after three days of treatment, it is a positive sign. However, it is essential to remain vigilant. The risk of sudden deterioration can still exist, particularly if there are underlying health concerns or if the virus behaves unpredictably. Medical professionals often advise patients to monitor their symptoms closely and seek medical attention if they notice any significant changes, such as difficulty breathing, persistent chest pain, confusion, or bluish lips or face.

Moreover, the phenomenon of "biphasic illness" has been observed in some COVID-19 patients, where individuals may initially improve and then experience a second wave of symptoms. This can occur approximately one week after the onset of symptoms, which is why continuous monitoring is crucial.
In terms of your anxiety about the potential for sudden worsening, it is understandable. Many patients share similar concerns, and it is important to communicate openly with your healthcare provider about any worries you may have. They can provide personalized advice based on your health history and current condition.

Additionally, it is worth noting that vaccination plays a significant role in reducing the risk of severe illness from COVID-19. Vaccines have been shown to decrease the likelihood of hospitalization and death, even in breakthrough infections. If you have not yet been vaccinated, discussing this with your healthcare provider may be beneficial, especially considering the evolving nature of COVID-19 variants.

In conclusion, while the risk of developing severe COVID-19 after initially mild symptoms exists, it is often influenced by various factors. Continuous monitoring of your health, maintaining communication with your healthcare provider, and considering vaccination are all important steps in managing your risk. Remember, while no one can predict the future with absolute certainty, being informed and proactive about your health can help you navigate this challenging situation more effectively.

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