Pulmonary Hypertension from Amberning and Antihistamine Interactions - Cardiology

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Hello, I would like to inquire about pulmonary hypertension caused by the sedative Amberning?


Hello, I would like to ask about my situation.
I accidentally took a sedative called Ambien along with an antihistamine, and since then, I have been experiencing increasing shortness of breath.
Initially, it wasn't so severe, but recently my heart has been racing.
What started as occasional shortness of breath has now escalated to the point where I experience it with any activity.
Sometimes, I even have palpitations that prevent me from sleeping.
Here are my symptoms:
1.
Shortness of breath while walking.
2.
Difficulty breathing.
3.
Frequent unexplained chest pain, with constant palpitations and a strong heartbeat.
4.
Increased respiratory distress.
5.
Loss of appetite.
6.
Persistent extreme fatigue.
7.
Occasional sharp chest pain and cold sweats.
8.
Occasionally feeling pressure in my lungs, as if something heavy is pressing on my back and chest.
9.
Occasional chest tightness, with blood oxygen levels dropping to seventy.
10.
Inability to go out; I become extremely breathless after just a few steps.
Could these symptoms be side effects of the medications leading to pulmonary hypertension? My blood pressure was previously 120, but now it is consistently around 150.

nv vivian, 40~49 year old female. Ask Date: 2022/10/11

Dr. Wu Xueming reply Cardiology


Medications do not cause pulmonary hypertension; it is recommended that you go to the hospital for further evaluation.

Reply Date: 2022/10/11

More Info


Pulmonary hypertension (PH) is a complex condition characterized by elevated blood pressure in the pulmonary arteries, which can lead to various symptoms, including shortness of breath, fatigue, and chest pain. Your concerns regarding the potential interactions between Amberning (a sedative) and antihistamines, and their possible contribution to your symptoms, are valid and warrant a thorough understanding.

Firstly, it is important to clarify that while certain medications can influence respiratory function and cardiovascular health, they do not directly cause pulmonary hypertension. However, they can exacerbate pre-existing conditions or lead to side effects that mimic or worsen symptoms associated with pulmonary hypertension. For instance, both sedatives and antihistamines can cause respiratory depression, especially in individuals with underlying lung issues or those who may be sensitive to these medications. This respiratory depression can lead to feelings of breathlessness and increased heart rate, particularly during physical exertion or even at rest.

Your symptoms, including increasing shortness of breath, palpitations, and chest pain, are concerning and suggest that you may be experiencing more than just medication side effects. The fact that your blood pressure has risen from 120 to 150 could indicate a stress response or an underlying cardiovascular issue that needs to be addressed. Elevated blood pressure, along with symptoms like fatigue, chest pain, and difficulty breathing, could suggest that your heart is working harder than normal, potentially due to increased resistance in the pulmonary circulation.

It is crucial to seek immediate medical attention for a comprehensive evaluation. A healthcare provider may recommend several diagnostic tests, including echocardiography, pulmonary function tests, and possibly a right heart catheterization, to assess the pressure in your pulmonary arteries and evaluate your heart's function. These tests will help determine whether you have pulmonary hypertension and its severity, as well as identify any other underlying conditions that may be contributing to your symptoms.

In the meantime, it is advisable to avoid any medications that you suspect may be causing adverse effects without consulting your healthcare provider. If you are experiencing severe symptoms, such as significant shortness of breath or chest pain, it is essential to seek emergency medical care.

In summary, while Amberning and antihistamines may not directly cause pulmonary hypertension, they can exacerbate respiratory and cardiovascular symptoms, particularly in sensitive individuals. Your symptoms warrant a thorough medical evaluation to rule out pulmonary hypertension and other potential cardiovascular issues. Please prioritize your health and seek medical attention promptly to address these concerning symptoms.

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