Abnormal CEA Levels: What You Need to Know - Gastroenterology and Hepatology

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Understanding abnormal levels of Carcinoembryonic Antigen (CEA) is crucial for individuals who may be at risk for certain cancers, particularly those with a family history or existing health conditions. CEA is a glycoprotein involved in cell adhesion, and its levels can be elevated in various malignancies, especially adenocarcinomas of the colon, pancreas, stomach, and lungs. However, it is important to note that CEA is not exclusively a cancer marker; it can also be elevated in benign conditions, such as inflammatory diseases, liver disease, and even in smokers.

In your case, the CEA levels have shown a concerning trend, increasing from 6.71 to 7.56 ng/ml over a relatively short period. While the reference range for CEA can vary slightly depending on the laboratory, levels above 5 ng/ml are generally considered elevated and warrant further investigation, especially in the context of your symptoms and medical history.

Given your previous gastrointestinal evaluations, including an endoscopy and colonoscopy, which revealed mild gastroesophageal reflux and gastritis but no significant findings, it is essential to consider other factors that could contribute to the rise in CEA levels. Conditions such as chronic inflammation, infections, or even benign tumors can lead to elevated CEA levels. Additionally, your diagnosis of irritable bowel syndrome (IBS) and the presence of polycystic ovaries may also play a role in your overall health status and CEA levels.

The small lung nodule identified in your CT scan should be monitored, as lung nodules can sometimes be benign or malignant. The fact that you have a family history of colorectal cancer and your elevated CEA levels necessitate a thorough evaluation. It is advisable to consult with an oncologist or a gastroenterologist who can assess your risk factors in detail and recommend appropriate follow-up tests, which may include repeat imaging studies or a biopsy if indicated.

In summary, while your CEA levels are elevated, it is crucial to interpret these results in the context of your overall health and medical history. Continuous monitoring and further diagnostic testing are essential to determine the underlying cause of the elevated CEA levels. It is also important to maintain open communication with your healthcare providers, who can guide you through the necessary steps for further evaluation and management. Regular screenings, especially given your family history, are vital for early detection and intervention if needed.