Abnormal eGFR: Insights into Kidney Function Issues - Internal Medicine

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Understanding abnormal eGFR (estimated Glomerular Filtration Rate) is crucial for assessing kidney function. Your recent lab results show a creatinine level of 0.84, BUN (Blood Urea Nitrogen) of 13, and an eGFR of 86.4, which is indeed within the normal range for kidney function. However, you mentioned that this value is considered "significantly abnormal," which may be a misunderstanding or miscommunication, as eGFR values above 60 typically indicate acceptable kidney function.

To clarify, eGFR is a calculated estimate of how well your kidneys are filtering blood. It is derived from your serum creatinine level, age, gender, and sometimes race. Normal eGFR values generally range from 90 to 120 mL/min/1.73 m², but values can vary based on individual factors. An eGFR of 86.4 suggests that your kidney function is still relatively good, although it is slightly below the optimal range.
Your previous results from two years ago showed an eGFR of 78, which indicates a decline in kidney function over time. However, this decline is not drastic, and your current eGFR still falls within a range that is not typically concerning. The presence of normal BUN and creatinine levels further supports the notion that your kidneys are functioning adequately.

Several factors can influence eGFR readings, including hydration status, muscle mass, and dietary protein intake. You mentioned having low muscle mass, which can affect creatinine levels since creatinine is a byproduct of muscle metabolism. In individuals with lower muscle mass, creatinine levels may be lower, potentially leading to a higher eGFR.
Regarding your cholesterol level of 232, while this is slightly elevated, it is essential to consider the context of your overall health, including your diet and lifestyle. Elevated cholesterol can be a risk factor for cardiovascular disease, which can indirectly affect kidney health. Therefore, maintaining a balanced diet, regular exercise, and monitoring your cholesterol levels are vital.

In terms of kidney health, it is crucial to focus on preventive measures rather than solely on eGFR numbers. Here are some recommendations:
1. Hydration: Ensure you are adequately hydrated, as dehydration can lead to temporary changes in kidney function.

2. Diet: Continue with a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. If you have concerns about phosphorus intake, particularly if you have any underlying kidney issues, consult with a healthcare provider or a dietitian for personalized advice.

3. Regular Monitoring: Keep track of your kidney function through regular check-ups, especially if you have risk factors such as high cholesterol or a family history of kidney disease.

4. Blood Pressure and Blood Sugar Control: Maintain healthy blood pressure and blood sugar levels, as hypertension and diabetes are significant risk factors for kidney disease.

5. Exercise: Engage in regular physical activity to support overall health, including kidney function.

6. Avoid Nephrotoxins: Be cautious with medications and substances that can harm the kidneys, such as non-steroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics.

In conclusion, while your eGFR has shown some decline, your current results indicate that your kidney function is still within a normal range. It is essential to maintain a healthy lifestyle and have regular check-ups to monitor your kidney health. If you have any concerns or experience symptoms such as swelling, changes in urination, or fatigue, consult your healthcare provider for further evaluation.