Medication Safety During Breastfeeding: What New Moms Should Know - Obstetrics and Gynecology

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Medication Consultation During Lactation


Hello, doctor.
I just gave birth a little over two weeks ago and have been breastfeeding daily.
Recently, I've been experiencing stomach cramps and diarrhea, so I consulted a gastroenterologist.
I would like to ask the obstetrician to review the following medications to see if they could affect my child through breast milk.
Thank you, doctor.
1.
Famotidine
2.
Peptidin
3.
Tagamet
4.
Domperidone
5.
Diotase
6.
Loperamide HCl
7.
KBT
8.
Dicyclomine HCl

Ms. P, 30~39 year old female. Ask Date: 2022/10/21

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it generally does not have an impact.
Wishing you good health.

Reply Date: 2022/10/21

More Info


When it comes to medication safety during breastfeeding, it is essential for new mothers to be well-informed about the potential effects of medications on their infants. Breastfeeding provides numerous benefits for both the mother and the baby, but it also raises concerns about the transfer of medications through breast milk. Here’s a detailed overview of the medications you mentioned and their implications for breastfeeding.

1. Famotidine: This medication is an H2 blocker used to treat conditions like gastroesophageal reflux disease (GERD) and ulcers. Studies have shown that famotidine is excreted in breast milk in small amounts. However, it is generally considered safe for breastfeeding mothers, as the amounts transferred to breast milk are unlikely to cause any adverse effects in infants.

2. Peptidin (likely referring to Diphenoxylate/Atropine): This medication is used to treat diarrhea. While it can be effective, it is important to note that it may cause sedation in infants if transferred through breast milk. Therefore, caution is advised, and it may be best to consult with a healthcare provider before using this medication while breastfeeding.

3. Tagamet (Cimetidine): Similar to famotidine, cimetidine is another H2 blocker. It is also excreted in breast milk, but the amount is considered low. While it is generally regarded as safe, some studies suggest that it may affect the infant's liver function if used in high doses. Therefore, it is advisable to use it under medical supervision.

4. Domperidone: This medication is used to treat nausea and vomiting and to enhance gastric motility. Domperidone is excreted in breast milk, but the amounts are typically low. However, there are concerns about its potential effects on the infant's heart rhythm. Therefore, it is recommended to use this medication cautiously and under the guidance of a healthcare professional.

5. Diotase (likely referring to Pancreatin): This is a digestive enzyme supplement used to aid digestion. It is generally considered safe for breastfeeding mothers, as it is not expected to have any significant effects on breast milk or the nursing infant.

6. Loperamide HCl: This medication is commonly used to treat diarrhea. It is minimally absorbed into the bloodstream and is excreted in very small amounts in breast milk. It is generally considered safe for breastfeeding mothers, but it is essential to monitor the infant for any signs of constipation or sedation.

7. KBT (likely referring to a combination of medications): Without specific details on the components of KBT, it is challenging to provide a definitive answer. It is crucial to consult with a healthcare provider regarding the safety of this combination during breastfeeding.

8. Dicyclomine HCl: This medication is used to treat irritable bowel syndrome and other gastrointestinal disorders. It can cause sedation and may affect the infant if transferred through breast milk. Therefore, it is generally recommended to avoid this medication while breastfeeding unless absolutely necessary and under medical supervision.

In summary, while many medications can be safely used during breastfeeding, it is crucial to consult with a healthcare provider before starting any new medication. Each medication's potential risks and benefits should be carefully weighed, especially considering the infant's age and health status. Additionally, monitoring the infant for any adverse effects is essential when a breastfeeding mother is taking medication. Always prioritize open communication with healthcare providers to ensure the safety and well-being of both mother and child.

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