Eye Drops for Floaters: Safety and Long-Term Use - Ophthalmology

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Hello Doctor, I have symptoms of floaters.
The doctor who prescribed medication gave me two types of eye drops, both of which are said to relieve fatigue and alleviate symptoms of eye redness.
One is a purple eye drop from the brand "Soothe," containing Fluorometholone 1mg and Tetryzoline Hydrochloride 0.25mg.
The other is a white and green eye drop from the brand "Aisiming," containing Neostigmine Methylsulfate 0.05mg.
I researched the ingredients online and found that the purple one contains a steroid.
I'm not very clear about the other one.
Can these two be used long-term? (Currently, I am using them four times a day.) If the eye drop containing steroids is used long-term, could it lead to glaucoma? Thank you for your help, Doctor.

Muzi Li, 20~29 year old female. Ask Date: 2022/10/24

Dr. He Jianxian reply Ophthalmology


This is classified as a low-dose corticosteroid.
Generally, high doses are more likely to cause glaucoma, and it typically requires prolonged use to induce this condition, usually over several months.
The above opinion is for reference.
Director He Jianxian, Ophthalmology Department, Nantou Hospital.

Reply Date: 2022/10/24

More Info


When it comes to the use of eye drops for conditions like floaters, it's essential to understand both the ingredients and the potential long-term effects of these medications. You mentioned that you have been prescribed two types of eye drops: one containing Fluorometholone and Tetryzoline Hydrochloride, and another containing Neostigmine Methylsulfate. Let's break down these components and their implications for long-term use.

Fluorometholone is a corticosteroid that is commonly used to reduce inflammation in the eye. While it can be effective for treating conditions such as chronic conjunctivitis or uveitis, long-term use of corticosteroids can lead to several side effects, including increased intraocular pressure, which can potentially lead to glaucoma. This is particularly concerning for individuals who may already be at risk for glaucoma or have a history of elevated eye pressure. Therefore, while Fluorometholone can be beneficial for short-term relief, it is generally not recommended for prolonged use without close monitoring by an eye care professional.

Tetryzoline Hydrochloride, on the other hand, is a vasoconstrictor that helps to relieve redness in the eyes by constricting blood vessels. While it can provide temporary relief from redness and irritation, frequent use can lead to rebound redness, where the eyes become redder once the medication is stopped. This can create a cycle of dependency on the drops for relief.

The second eye drop you mentioned, Neostigmine Methylsulfate, is primarily used to improve muscle function in the eye and is not typically associated with the same risks as corticosteroids. However, it is essential to use this medication under the guidance of a healthcare provider, as it is not intended for routine maintenance or long-term use without a specific indication.

Given your situation with floaters, it's crucial to approach the use of these medications with caution. While they may provide temporary relief from symptoms like eye fatigue and redness, relying on them long-term can lead to complications, especially with the corticosteroid component. It is advisable to follow your doctor's instructions closely and to have regular check-ups to monitor your eye health, particularly if you are using these drops frequently.

In terms of safety, it is essential to communicate with your eye care provider about any concerns you have regarding the long-term use of these medications. They may suggest alternative treatments or strategies to manage your symptoms without the risks associated with prolonged corticosteroid use. Additionally, lifestyle changes such as reducing screen time, taking regular breaks during prolonged visual tasks, and using artificial tears can help alleviate symptoms of eye fatigue without the need for medicated eye drops.

In summary, while both types of eye drops can provide symptomatic relief, their long-term use should be carefully monitored. The corticosteroid-containing drops pose a risk of increased intraocular pressure and potential glaucoma, while the other drops may lead to rebound redness if used excessively. Always consult with your eye care professional before making any changes to your medication regimen, and ensure that you are receiving appropriate follow-up care to safeguard your eye health.

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