Shortness of Breath After Taking Heart Medications - Cardiology

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Hello, I feel very short of breath after taking the medication?


Hello, I have been experiencing shortness of breath recently.
Yesterday, I took half a dose of Soredit (PerSantin) and half a dose of Norvasc (Amlodipine), and now I feel weak and constantly sleepy.
I also experience shortness of breath when walking.
Could this be related to a drug interaction causing side effects?

He Tong, 40~49 year old female. Ask Date: 2022/11/04

Dr. He Dongjin reply Cardiology


Hello, each person's constitution is different, so it's hard to say.
Theoretically, such a low dose taken only once is unlikely to cause significant side effects.
If you feel uncomfortable, it's best to stop taking it.
Changhua Hospital cares about you.

Reply Date: 2022/11/04

More Info


Shortness of breath and fatigue after taking heart medications can indeed be concerning, and it’s important to understand the potential causes and implications. Based on your description, it seems you are experiencing significant side effects after taking a combination of medications, specifically half a dose of Persantin (Dipyridamole) and half a dose of Norvasc (Amlodipine).
Both of these medications are commonly prescribed for heart-related issues, but they can have side effects that may contribute to your symptoms. Dipyridamole is a vasodilator, which means it works by widening blood vessels to improve blood flow. While it can be effective in preventing blood clots, it may also lead to side effects such as dizziness, headache, and, in some cases, shortness of breath. Amlodipine, on the other hand, is a calcium channel blocker that helps lower blood pressure and reduce chest pain. Common side effects include swelling, dizziness, and fatigue.
The combination of these two medications can potentially lead to an additive effect on blood pressure, which might explain your feelings of weakness and fatigue. If your blood pressure drops too low, it can result in symptoms such as lightheadedness, fatigue, and shortness of breath, especially during physical activity.
It’s also worth considering that shortness of breath can be a multifactorial issue. If you have underlying heart conditions, such as mitral valve prolapse or pulmonary hypertension, these could exacerbate your symptoms when combined with the effects of your medications. Additionally, anxiety and stress can also contribute to feelings of breathlessness, which may be heightened if you are concerned about your health.

Given your symptoms, it is crucial to consult with your healthcare provider. They may want to evaluate your current medication regimen and consider adjusting the dosages or switching to alternative medications that may have a more favorable side effect profile for you. It’s also essential to monitor your blood pressure regularly, as both medications can affect it, and ensure it remains within a safe range.

In the meantime, here are some general recommendations to help manage your symptoms:
1. Rest and Hydration: Ensure you are well-hydrated and take breaks when needed. Avoid strenuous activities until you have discussed your symptoms with your doctor.

2. Monitor Symptoms: Keep a log of your symptoms, including when they occur and their severity. This information can be valuable for your healthcare provider in determining the best course of action.

3. Avoid Triggers: If you notice that certain activities or situations exacerbate your shortness of breath, try to avoid them until you have a clearer understanding of your condition.

4. Medication Review: Discuss with your doctor the possibility of reviewing your medications. There may be alternative treatments available that can help manage your heart condition without causing significant side effects.

5. Follow-Up Appointments: Regular follow-ups with your cardiologist are essential to monitor your heart health and adjust treatment as necessary.

In conclusion, while it is possible that your symptoms are related to the medications you are taking, it is essential to have a thorough evaluation by your healthcare provider to rule out any serious underlying issues and to ensure that your treatment plan is appropriate for your specific condition. Your health and well-being are paramount, and open communication with your healthcare team is key to managing your heart health effectively.

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