White Blisters on the Corona: Causes and Concerns in Urology - Urology

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White blisters on the coronal sulcus?


Hello Doctor, last week while showering, I noticed a white, blister-like growth in the coronal sulcus area.
It is neither painful nor itchy.
I visited a clinic, but the on-call physician said it did not resemble common sexually transmitted infections or pearly penile papules.
It has been nearly four months since my last sexual encounter.
The doctor prescribed a strong topical ointment for me to apply and advised me to observe it for a week.
However, today I noticed that I have been experiencing some frequency in urination (I haven't drunk water for three hours and felt sleepy, yet I went to the bathroom three times) and there is a slight burning sensation in the urethra during urination.
I also have some concerns regarding the ointment, as I have G6PD deficiency.
The ingredient list of the strong topical ointment includes 10 mg of dl-Menthol and 5 mg of dl-Camphor per gram.
Although I have not experienced any allergic reactions after applying it over the past few days, I would like to ask if I might be suffering from balanitis or if it could be a reaction to the ointment? (Attached is a photo of the white growth) https://ppt.cc/f574Px Thank you, Doctor, for taking the time to respond.

ROU, 20~29 year old female. Ask Date: 2022/11/09

Dr. Du Shixi reply Urology


Hello: Unlike a blister, it may be localized edema.
Keep the area clean and dry, and seek medical attention if there are any changes.
Wishing you good health.

Reply Date: 2022/11/09

More Info


The appearance of white blisters or bumps on the corona of the penis can be concerning, especially when accompanied by symptoms such as increased urinary frequency and a burning sensation during urination. While you have already consulted a physician who suggested that these symptoms do not appear to be typical of common sexually transmitted infections (STIs) or pearly penile papules, it is essential to consider a few potential causes and the implications of your symptoms.

First, the white blisters you describe could be a manifestation of several conditions. One possibility is a benign condition such as pearly penile papules, which are small, harmless bumps that often appear around the corona and are not associated with any disease. However, since your physician has ruled out common STIs, other conditions such as balanitis (inflammation of the glans), folliculitis (inflammation of hair follicles), or even a mild allergic reaction to products used in the genital area should be considered.

The burning sensation during urination and increased frequency could indicate a urinary tract infection (UTI) or irritation of the urethra, which may or may not be related to the white blisters. UTIs can occur independently of any visible lesions and may present with symptoms such as urgency, frequency, and dysuria (painful urination). Given that you have experienced these symptoms, it would be prudent to perform a urinalysis to rule out any infection.

Regarding the topical medication you are using, it is important to be cautious, especially considering your history of favism (a condition related to G6PD deficiency). The ingredients in the ointment, such as menthol and camphor, can sometimes cause irritation or allergic reactions in sensitive individuals. While you have not experienced any immediate adverse reactions, it is still possible that the medication could be contributing to your symptoms. If the burning sensation persists or worsens, or if you notice any new symptoms, it would be wise to discontinue the use of the ointment and consult your healthcare provider.

In summary, while the white blisters may not be indicative of a serious condition, the accompanying urinary symptoms warrant further investigation. It is advisable to follow up with a urologist for a thorough examination, including a urinalysis and possibly imaging studies if necessary. This will help determine the underlying cause of your symptoms and guide appropriate treatment. Additionally, if you experience any worsening of symptoms, such as fever, increased pain, or changes in the appearance of the blisters, seek medical attention promptly.

In conclusion, while the initial assessment by your physician is reassuring, your symptoms of increased urinary frequency and burning sensation during urination should not be ignored. A comprehensive evaluation is essential to ensure that any potential issues are addressed promptly and effectively.

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