Fecal Occult Blood Testing and Its Accuracy Concerns - Surgery

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Regarding fecal occult blood testing?


Hello, Doctor: I would like to ask you a few questions: 1.
I often experience constipation and have difficulty with bowel movements.
Therefore, around July of this year, I paid out of pocket for a fecal occult blood test.
However, I was taking a stool softener at that time, which made my stool very loose, and I was unable to collect a significant amount of sample (only a small amount was collected on the sampling device).
The result of the test came back normal.
Could the small amount collected have affected the accuracy of the test results? Thank you.
2.
Additionally, since mid-October of this year, I have been experiencing a dull, aching discomfort in my lower right abdomen.
I went to a gynecologist who performed an ultrasound and said everything was fine, and then referred me to a gastroenterologist.
The gastroenterologist also performed an ultrasound and noted some swelling in my intestines, possibly indicating inflammation, and prescribed me some antibiotics.
However, after completing the course, I still occasionally feel some discomfort in my lower right abdomen, but it is not constant; it comes and goes.
Should I repeat the fecal occult blood test, or do you have any other recommendations for me? Thank you very much.

Niming, 40~49 year old female. Ask Date: 2022/11/11

Dr. Zhang Shuhao reply Surgery


1.
A positive fecal occult blood test indicates a high likelihood of polyps or colorectal lesions, but it should only be used as a screening tool and not as a diagnostic instrument.
2.
It is not recommended to repeat the fecal occult blood test; if gastrointestinal symptoms are present, a colonoscopy is advised to rule out colorectal lesions.

Reply Date: 2022/11/11

More Info


Fecal occult blood testing (FOBT) is a crucial screening tool used to detect hidden blood in the stool, which can be an early sign of gastrointestinal issues, including colorectal cancer. Understanding the accuracy and implications of this test is essential, especially in the context of your concerns regarding sample collection and subsequent gastrointestinal symptoms.

1. Sample Collection and Accuracy: You mentioned that during your FOBT in July, you were experiencing constipation and used a stool softener, resulting in a loose stool. It's important to note that the accuracy of the FOBT can indeed be influenced by the amount and quality of the sample collected. The test typically requires a sufficient amount of stool to detect any traces of blood accurately. If only a small amount of stool was collected, as you described, it could potentially lead to a false-negative result. This means that even if there was blood present, the test might not have detected it due to insufficient sample size. Therefore, if you have concerns about the accuracy of your previous test, it may be prudent to repeat the FOBT, especially considering your ongoing gastrointestinal symptoms.

2. Ongoing Symptoms and Further Evaluation: You reported experiencing discomfort in your right lower abdomen, which has persisted despite antibiotic treatment for suspected inflammation. While the ultrasound results from both your gynecologist and gastroenterologist indicated no significant issues, the fact that you are still experiencing discomfort warrants further investigation. It is not uncommon for gastrointestinal issues to manifest as intermittent pain, and this can sometimes be associated with conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or even functional gastrointestinal disorders.

Given your symptoms and the previous FOBT results, here are some recommendations:
- Repeat the FOBT: Since your initial test may not have been fully representative due to the small sample size, repeating the FOBT could provide more reliable information regarding the presence of occult blood.

- Consult a Gastroenterologist: If your symptoms persist, it may be beneficial to follow up with a gastroenterologist for a more comprehensive evaluation. They may recommend additional tests, such as a colonoscopy, especially if there is a family history of colorectal cancer or if your symptoms worsen.

- Monitor Symptoms: Keep a detailed record of your symptoms, including when they occur, their intensity, and any associated factors (like diet or stress). This information can be valuable for your healthcare provider in determining the next steps.

- Dietary Considerations: Since you mentioned experiencing constipation, consider discussing dietary changes that could help regulate your bowel movements. Increasing fiber intake, staying hydrated, and regular physical activity can often alleviate constipation.

- Follow-Up Care: Ensure that you have a follow-up plan with your healthcare providers to monitor your symptoms and any new developments. Regular check-ups can help catch any potential issues early.

In summary, while your initial FOBT result was normal, the concerns regarding sample size and ongoing abdominal discomfort suggest that further evaluation is warranted. Repeating the test and consulting with a gastroenterologist can help clarify your situation and ensure that any underlying issues are addressed promptly. Your health and peace of mind are paramount, so don't hesitate to seek further medical advice.

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