Your Blood Test Results: High CPK and Eosinophil Levels Explained

Blood test

Hello Doctor, I went to the emergency room yesterday and had a blood test done.
My results are as follows: Hb 17.0, HCT 50.1, MCH 31.8, MCHC 34.0, MCV 94, MPV 9.0, Platelet count 156, RBC count 5.36, RDW 12.7, WBC count 45, Eosinophil 1.5, Lymphocyte 39.5, Monocyte 7.9, Basophil 3.0, Neutrophil 48.1, CPK 390.
The highlighted value is CPK and Basophil.
I read online that CPK is related to exercise; I work out every day, and I'm not sure if this is a concern.
I would also like to ask why my basophil count is elevated at 3.0.
What could be the reason? I found online that it might be polycythemia, which is making me very worried.
Additionally, are my Hb and HCT levels also elevated? I read that the standard values indicate Hb > 16.5 and HCT > 50 as polycythemia, which is causing me anxiety and affecting my ability to eat and sleep.
Could these results be related to my dislike of drinking water, leading to concentrated blood? I'm really concerned and would appreciate your clarification.
Thank you.

Enen, 20~29 year old female. Ask Date: 2022/11/11

Dr. Gao Jiankai reply Internal Medicine

Hello, thank you for your question.
Elevated CPK levels can indeed be related to vigorous exercise, and given your age, this is the most likely reason.
Basophils are a type of white blood cell associated with allergies, and their proportion in the total white blood cell count is relatively low; 3% is only slightly elevated, which is not concerning to me.
If you are worried, you can follow up in a few months, such as after three months.
Lastly, for someone your age, both Hb (hemoglobin) and Hct (hematocrit) levels may be higher, especially if there is insufficient hydration, which can lead to elevated values.
Therefore, please ensure adequate hydration after exercise.
If you are still concerned, you can also have a recheck in three months.
Best regards from the Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare.

Reply Date: 2022/11/11

More Info

Understanding your blood test results can be quite daunting, especially when you come across values that seem abnormal or concerning. Let's break down the results you've provided, focusing on the elevated CPK (Creatine Phosphokinase) and eosinophil levels, as well as the implications of your hemoglobin (Hb) and hematocrit (Hct) values.

Elevated CPK Levels
Your CPK level is reported at 390 U/L, which is considered elevated. CPK is an enzyme found in the heart, brain, and skeletal muscles. Elevated levels can indicate muscle damage, which is often associated with intense physical activity, such as weightlifting or endurance training. Since you mentioned that you work out daily, it is likely that your elevated CPK is a result of muscle strain or damage from your exercise routine.
However, it's essential to monitor this level, especially if you experience symptoms like muscle pain, weakness, or any unusual signs. If your CPK levels remain elevated over time or if you experience concerning symptoms, it would be prudent to consult with a healthcare professional for further evaluation.

Eosinophil Levels
Your eosinophil count is reported at 1.5%, which is within the normal range for most laboratories (typically 1-4%). Eosinophils are a type of white blood cell involved in the body's immune response, particularly in allergic reactions and parasitic infections. A slight increase in eosinophils can occur due to allergies, asthma, or certain infections, but your value does not indicate a significant concern.

You mentioned a previous concern about a higher eosinophil count of 3.0%. While this is slightly elevated, it is not uncommon and can be influenced by various factors, including allergic reactions or environmental exposures. If you have a history of allergies or asthma, this could explain the fluctuation in your eosinophil levels.

Hemoglobin and Hematocrit Levels
Your hemoglobin level is 17.0 g/dL and hematocrit is 50.1%. These values are indeed on the higher side of the normal range, and as you noted, levels above 16.5 g/dL for hemoglobin and 50% for hematocrit can suggest polycythemia, a condition characterized by an increased number of red blood cells. However, it is crucial to consider hydration status when interpreting these results. Dehydration can lead to hemoconcentration, where the blood appears more concentrated due to a lower plasma volume, which can artificially elevate hemoglobin and hematocrit levels.

If you are not drinking enough water, this could explain your elevated values. It is essential to stay well-hydrated, especially if you are engaging in regular physical activity. Drinking adequate fluids can help maintain normal blood volume and prevent misleading lab results.

Conclusion
In summary, your elevated CPK levels are likely related to your exercise routine, while your eosinophil levels are within a normal range and not a cause for concern. Your hemoglobin and hematocrit levels may be elevated due to dehydration rather than an underlying health issue. It is always best to discuss your results with a healthcare provider who can consider your overall health, symptoms, and lifestyle factors. Regular follow-up and monitoring can help ensure that any changes in your blood work are appropriately addressed. Remember to stay hydrated and maintain a balanced diet to support your overall health and well-being.

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