Managing Chronic Bacterial Prostatitis: Antibiotics and Alpha Blockers - Urology

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Treatment of Chronic Bacterial Prostatitis


Hello Doctor: I previously underwent a digital rectal examination and cultured Escherichia coli.
I am currently on antibiotic treatment.
My main symptoms include pain at the base of the penis and in the lower abdomen, but I experience infrequent urination and nocturia.
The doctor prescribed alpha-blockers, but I have noticed severe dizziness and nasal congestion after taking them, even with different medications.
I would like to ask the doctor if it is possible to discontinue the alpha-blockers if there are no urinary obstruction symptoms.
I understand that the primary function of these blockers is to assist with urination.
(I am still continuing with antibiotics and anti-inflammatory medications.) I am concerned that not taking the alpha-blockers may affect my treatment.
Thank you, Doctor!

zackk, 20~29 year old female. Ask Date: 2022/11/12

Dr. Du Shixi reply Urology


Hello: Personal opinions can be set aside, but it is advisable to consult the prescribing physician.
Wishing you good health.

Reply Date: 2022/11/12

More Info


Managing chronic bacterial prostatitis can be quite complex, especially when it comes to the choice of antibiotics and the use of alpha-blockers. Your situation, characterized by pain in the perineal area and lower abdomen, along with a diagnosis of E. coli infection, is not uncommon in cases of chronic prostatitis.

Antibiotic Treatment
The first line of treatment for bacterial prostatitis typically involves antibiotics. In your case, since you have been prescribed antibiotics for E. coli, it is crucial to ensure that the antibiotic chosen is effective against the specific strain of bacteria you have. The duration of antibiotic therapy for chronic bacterial prostatitis is often longer than for acute infections, sometimes extending to 4-6 weeks or more, depending on the severity of the infection and the patient's response to treatment.

Alpha-Blockers
Alpha-blockers are often prescribed to help alleviate urinary symptoms associated with prostatitis, such as urinary frequency and urgency. They work by relaxing the muscles in the bladder neck and prostate, which can help improve urine flow and reduce symptoms. However, as you have experienced, these medications can have side effects, including dizziness and nasal congestion.
Given your current symptoms, particularly the absence of significant urinary obstruction, it may be reasonable to consider discontinuing the alpha-blocker. The primary goal of treatment is to alleviate your symptoms while effectively managing the infection. If you are not experiencing significant urinary difficulties, stopping the alpha-blocker could be an option. However, it is essential to discuss this with your healthcare provider before making any changes to your medication regimen.

Monitoring and Follow-Up
It is also important to monitor your symptoms closely. If you notice a worsening of your symptoms after stopping the alpha-blocker, you may need to reconsider its use or explore alternative medications that might have fewer side effects. Additionally, regular follow-ups with your healthcare provider are crucial to assess the effectiveness of the antibiotic treatment and to make any necessary adjustments.


Potential Risks and Considerations
While it is understandable to be concerned about the impact of stopping the alpha-blocker on your treatment, it is also essential to weigh the benefits against the side effects you are experiencing. Chronic prostatitis can be a challenging condition to manage, and finding the right balance of medications is key.
If you have any concerns about the effectiveness of your current antibiotic treatment or the management of your symptoms, it may be beneficial to seek a second opinion or consult a specialist in urology or infectious diseases. They can provide additional insights and may suggest alternative treatment options or further diagnostic evaluations, such as imaging studies or additional laboratory tests, to ensure that there are no underlying issues contributing to your symptoms.


Conclusion
In summary, while alpha-blockers can be beneficial for managing urinary symptoms in chronic bacterial prostatitis, their use should be tailored to the individual patient's needs and tolerability. If you are not experiencing significant urinary obstruction, it may be appropriate to discuss discontinuing the medication with your healthcare provider. Continuous monitoring and open communication with your healthcare team will be vital in managing your condition effectively.

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