Mitral Valve Prolapse and Myocardial Ischemia Symptoms - Cardiology

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There is mitral valve prolapse with mild regurgitation?


Hello, doctor.
Two years ago, I was diagnosed with mitral valve prolapse and mild regurgitation.
Last month, I visited a nearby hospital's cardiology department due to persistent left chest pain and shortness of breath.
The electrocardiogram report indicated myocardial ischemia.
Should I pursue further treatment for the symptoms of myocardial ischemia? Currently, I am taking Sotalol 10 mg.
Thank you.
The electrocardiogram report shows a heart rate of 78, R-R interval of 769 ms, QRS duration of 93 ms, QRS axis of 74, PR interval of 163 ms, QT interval of 350 ms, QTc of 400 ms, and RV5 (11.0) + SV1 (8.2) = 19.2 mm, with a determination of moderate abnormality and an analysis result indicating myocardial ischemia with ST segment depression of -0.8 mm.

Raylene, 20~29 year old female. Ask Date: 2022/11/14

Dr. Wu Xueming reply Cardiology


Due to your young age and lack of chronic diseases, your risk of developing heart disease is low.
Many factors in life can contribute to this situation, such as emotions, stress, irregular sleep patterns, or excessive intake of caffeinated beverages.
It is advisable to adjust your lifestyle and engage in regular exercise.
However, if symptoms persist, it is still recommended to undergo a stress echocardiogram at a hospital.

Reply Date: 2022/11/14

More Info


Mitral Valve Prolapse (MVP) is a condition where the mitral valve does not close properly, which can lead to mitral regurgitation (backward flow of blood into the left atrium). While many individuals with MVP may remain asymptomatic, some can experience symptoms such as palpitations, chest pain, and shortness of breath. In your case, the presence of mild mitral regurgitation alongside your symptoms of persistent left chest pain and dyspnea (shortness of breath) warrants careful evaluation.

Myocardial ischemia occurs when blood flow to the heart muscle is reduced, preventing it from receiving adequate oxygen. This can manifest as chest pain (angina), shortness of breath, fatigue, and other symptoms. The electrocardiogram (ECG) findings you mentioned, particularly the ST-segment depression (ST -0.8mm), suggest that there is indeed some degree of myocardial ischemia occurring, which is a concerning sign.

Given your history of MVP and the recent symptoms, it is crucial to address the potential for ischemic heart disease. The fact that you are already on medication (生達心律錠, likely a beta-blocker or similar) indicates that your healthcare provider is taking steps to manage your symptoms and any underlying conditions. However, the presence of myocardial ischemia on your ECG suggests that further evaluation and possibly treatment may be necessary.

Here are some considerations regarding your situation:
1. Further Diagnostic Testing: It may be beneficial to undergo additional tests such as a stress test (either exercise or pharmacological) or a myocardial perfusion scan to assess the extent of ischemia and the overall function of your heart. These tests can help determine if there are significant blockages in the coronary arteries that need to be addressed.

2. Cardiology Consultation: Since you have experienced chest pain and shortness of breath, it is advisable to follow up with a cardiologist. They can provide a comprehensive evaluation, including reviewing your ECG results, assessing your symptoms, and determining the need for further interventions such as coronary angiography.

3. Management of Symptoms: Depending on the findings from further testing, your treatment plan may include adjustments to your current medication regimen, lifestyle modifications (such as diet and exercise), and possibly more invasive procedures if significant coronary artery disease is identified.

4. Monitoring and Follow-Up: Regular follow-up appointments with your healthcare provider are essential to monitor your condition, especially given the symptoms you are experiencing. This will allow for timely adjustments to your treatment plan as needed.

In summary, while MVP itself may not directly cause myocardial ischemia, the combination of your symptoms and the ECG findings suggests that further evaluation is warranted. It is important to work closely with your healthcare provider to ensure that any underlying issues are addressed and to optimize your treatment plan for both your MVP and any potential ischemic heart disease.

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