Medication Withdrawal in Bipolar Disorder Treatment - Psychiatry

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Drug withdrawal


Hello Doctor,
1.
I was diagnosed with bipolar disorder six months ago, which I believe was triggered by my habitual alcohol abuse.
During a drinking episode, I had a disagreement with my family and broke a glass in the house, which led to me being forcibly hospitalized.
At that time, the doctor only listened to my family and did not allow me to explain, resulting in a one-month hospitalization.
I have always felt that my emotional issues were due to my alcohol abuse rather than bipolar disorder.
Is it possible that this was a misdiagnosis?
2.
I have been on medication for six months, and my mood has stabilized, but the side effects of the medication are affecting my attention at work (I am a crane operator).
The doctor has been reluctant to help me taper off the medications, which include (1.
Sertraline 60 mg), (2.
Divalproex sodium enteric-coated tablets 200 mg), and (3.
Omeprazole delayed-release tablets 200 mg).
I have tried stopping the medications before, but I was unable to sleep at all that night, and I can only manage to stop for two days before I can't tolerate it anymore (even when I am very tired, I still can't sleep, and sleeping pills don't help much).
What can I do if I want to taper off the medications on my own? Thank you, Doctor.

Ni Ke, 30~39 year old female. Ask Date: 2022/11/22

Dr. Qiu Junda reply Psychiatry


Hello.
I also hope you do not stop your medication on your own.
However, the three medications you mentioned theoretically do not have addictive properties.
The one that is more likely to help with sleep is: Quetiapine extended-release film-coated tablets 200 mg.
You may try taking half a tablet of this medication first.

Reply Date: 2022/11/22

More Info


Understanding medication withdrawal in the context of bipolar disorder treatment is a complex issue that requires careful consideration of both the psychological and physiological aspects of the condition and the medications used.
1. Misdiagnosis Concerns: It is not uncommon for individuals with a history of substance abuse, such as alcohol, to be misdiagnosed with bipolar disorder. Alcohol can significantly affect mood and behavior, leading to symptoms that may mimic those of bipolar disorder, such as mood swings, irritability, and impulsive actions. The key factor in distinguishing between the two is the persistence and pattern of mood symptoms over time. If your mood swings were primarily triggered by alcohol use and not present when sober, it may suggest that the underlying issue is related to substance use rather than a primary mood disorder. However, a thorough evaluation by a mental health professional is necessary to clarify this diagnosis. It is essential to communicate your concerns with your healthcare provider, who can reassess your diagnosis and treatment plan.

2. Medication Side Effects and Withdrawal: The medications you mentioned—(1) Sertraline (欣樂膠囊), (2) Lamotrigine (帝拔癲腸溶錠), and (3) Quetiapine (潰益平持續藥效膜衣錠)—are commonly used to manage bipolar disorder. While they can be effective in stabilizing mood, they can also cause side effects, including drowsiness, cognitive impairment, and difficulties with attention, which can be particularly concerning for someone in a safety-sensitive job like crane operation.
If you are considering discontinuing your medication, it is crucial to do so under the guidance of your healthcare provider. Abruptly stopping medication can lead to withdrawal symptoms, including insomnia, mood instability, and a potential return of manic or depressive episodes. Here are some steps you can take:
- Consult Your Doctor: Before making any changes to your medication regimen, have an open discussion with your psychiatrist or prescribing physician. Express your concerns about side effects and your desire to taper off the medication. They can provide guidance on the safest way to do this.

- Gradual Tapering: If your doctor agrees that tapering off the medication is appropriate, they will likely recommend a gradual reduction in dosage rather than stopping abruptly. This approach helps minimize withdrawal symptoms and allows your body to adjust to lower levels of the medication.

- Monitor Symptoms: As you taper off the medication, keep a close eye on your mood and any withdrawal symptoms. It may be helpful to maintain a mood diary to track changes in your emotional state, sleep patterns, and any side effects you experience.

- Alternative Strategies: In addition to medication, consider exploring other strategies to manage your mood and improve your focus. These may include psychotherapy (such as cognitive-behavioral therapy), lifestyle changes (like regular exercise, a balanced diet, and good sleep hygiene), and support groups for individuals with bipolar disorder or substance use issues.

- Emergency Plan: If you experience severe mood swings or suicidal thoughts during the withdrawal process, it is crucial to seek immediate help from a mental health professional or emergency services.

In conclusion, while it is understandable to want to discontinue medication due to side effects, it is essential to approach this process cautiously and under medical supervision. Bipolar disorder is a chronic condition that often requires ongoing management, and finding the right balance between effective treatment and manageable side effects is key to maintaining stability and quality of life.

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