Post-COVID Complications: Pleural Effusion and Back Pain - Pulmonology

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Pleural effusion, pleural fluid accumulation, coronavirus?


Hello Doctor: My aunt was diagnosed with COVID-19 and a few days after her quarantine ended, she suddenly experienced severe lower back and waist pain.
She has not been vaccinated.
We took her to a new infectious disease specialist, who referred us to an orthopedic doctor and prescribed some pain medication.
However, after a month, her condition worsened to pleural effusion, with only one-third of her lung capacity remaining, blood oxygen levels at 87, and hemoglobin at 7.
Family and friends believe this is atypical pneumonia caused by COVID-19.
I have also seen case reports in Taiwanese medical journals indicating that lower back pain can be an atypical extrapulmonary symptom of pneumonia.
The hospital stated that my aunt has multiple bacterial infections in her lungs, and the fluid extracted was bright red blood.
The bacterial cultures have been ongoing for nearly two weeks, and it has been almost a month without resolving the bacterial issue.
Could this delay lead to more complications, such as lung adhesions that are harder to treat? I have seen many studies linking this to COVID-19.
Can you provide us with any advice? It is heartbreaking to see our family suffer.

JAYA, 50~59 year old female. Ask Date: 2022/11/22

Dr. Wu Yingxun reply Pulmonology


Hello: Pleural effusion does not always yield bacterial cultures.
Typically, broad-spectrum antibiotics are used to treat the bright red effusion, and there may be a suspicion of malignant effusion, which can be differentiated through pleural biopsy.
Additionally, severe COVID-19 can also lead to pleural effusion as a complication.

Reply Date: 2022/11/22

More Info


Post-COVID complications, particularly pleural effusion and back pain, have become increasingly recognized as significant issues following COVID-19 infection. Your aunt's situation, involving severe back pain and subsequent pleural effusion, raises several important points regarding the potential sequelae of COVID-19 and the complexities of managing such cases.

Firstly, it is essential to understand that COVID-19 can lead to a variety of complications, even after the acute phase of the illness has resolved. The virus can cause inflammation and damage to various organs, including the lungs, which may result in conditions such as pneumonia and pleural effusion. In your aunt's case, the back pain she experienced could be related to the underlying lung issues. It is not uncommon for patients with lung infections to report referred pain in the back, as the diaphragm and pleura are innervated by nerves that can cause pain to be perceived in the back.

The development of pleural effusion, which is the accumulation of fluid in the pleural space surrounding the lungs, can occur due to several reasons, including infection, inflammation, or malignancy. In the context of COVID-19, it is often related to pneumonia or other pulmonary complications. The fact that your aunt has not been vaccinated may also play a role in her susceptibility to severe complications from COVID-19, as vaccination has been shown to reduce the severity of illness and the risk of long-term complications.

Regarding the bacterial infection noted in her lungs, it is crucial to address this promptly. The presence of multiple bacteria and the extraction of bright red fluid suggest that there may be a significant infection that requires targeted antibiotic therapy. The delay in resolving this infection can indeed lead to further complications, such as lung adhesions or empyema, which can complicate treatment and recovery. It is vital for her healthcare team to perform thorough investigations, including imaging studies and possibly bronchoscopy, to identify the specific pathogens involved and tailor the antibiotic treatment accordingly.

In terms of management, it is essential to ensure that your aunt receives comprehensive care. This includes:
1. Close Monitoring: Regular follow-ups with her healthcare providers to monitor her respiratory status and response to treatment.

2. Antibiotic Therapy: Ensuring that she is on appropriate antibiotics based on culture results. If the bacteria are resistant to initial treatments, adjustments may be necessary.

3. Supportive Care: This may include oxygen therapy to manage her low blood oxygen levels and possibly diuretics if fluid overload is present.

4. Physical Therapy: Once her acute symptoms are managed, physical therapy may help improve her mobility and reduce pain.

5. Multidisciplinary Approach: Engaging specialists such as pulmonologists, infectious disease experts, and possibly pain management specialists to address her complex needs.

Lastly, it is crucial to maintain open communication with her healthcare team. If you feel that her condition is not improving or if there are concerns about the treatment plan, do not hesitate to seek a second opinion or ask for a referral to a specialist who can provide more targeted care.

In conclusion, your aunt's case highlights the importance of recognizing and addressing post-COVID complications, particularly when they manifest as severe symptoms like back pain and pleural effusion. With appropriate medical intervention and supportive care, there is hope for recovery, but it requires a coordinated effort from her healthcare providers.

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