Laser Surgery for Retinal Holes: Safety Concerns During Chemotherapy - Ophthalmology

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Retinal laser therapy


Hello Doctor, I am a breast cancer patient currently undergoing chemotherapy.
Recently, during an eye examination, a retinal tear was found.
I saw an ophthalmologist two weeks ago, and they scheduled me for laser surgery in early December.
At that time, I mentioned to the doctor that I am undergoing chemotherapy, and they indicated that it would not affect the procedure.
However, during my outpatient visit before chemotherapy yesterday, my white blood cell count was 2300.
I still received chemotherapy yesterday because the oncologist felt that my overall condition was good.
Now, I am concerned whether it is safe to undergo laser surgery with such a low white blood cell count.
Is there a risk of infection? Thank you for your help!

Youyou, 50~59 year old female. Ask Date: 2022/11/23

Dr. Cai Wenyuan reply Ophthalmology


The doctor indicated that it will not have an impact, and if necessary, it should be possible.

Reply Date: 2022/11/23

More Info


Laser surgery for retinal holes, particularly in patients undergoing chemotherapy, raises several important safety concerns that must be carefully considered. As a patient with breast cancer currently undergoing chemotherapy, your situation necessitates a thorough understanding of both the risks associated with laser surgery and the implications of your chemotherapy treatment on your overall health and recovery.

First and foremost, it is essential to recognize that chemotherapy can significantly impact your immune system. One of the most common side effects of chemotherapy is leukopenia, which is a reduction in the number of white blood cells (WBCs). A low white blood cell count, such as your reported level of 2300 cells per microliter (normal ranges typically being between 4,000 to 11,000 cells per microliter), can increase your susceptibility to infections. This is particularly concerning in the context of any surgical procedure, including laser surgery, where the risk of infection could be heightened due to the potential for exposure to pathogens.

In your case, the decision to proceed with laser surgery should involve a careful evaluation of your current health status, including your white blood cell count, overall physical condition, and the urgency of addressing the retinal hole. While your oncologist has deemed your mental and physical state satisfactory for chemotherapy, it is crucial to have a collaborative discussion with both your oncologist and your ophthalmologist. They can provide insights into whether your current health status allows for a safe surgical procedure.

The laser surgery itself is generally considered safe and effective for treating retinal holes, but the presence of a compromised immune system can complicate matters. If your white blood cell count is low, there is a risk that your body may not respond adequately to any potential infection that could arise from the procedure. Additionally, healing may be slower, and the risk of complications could be increased.

Moreover, it is important to consider the timing of the surgery in relation to your chemotherapy cycles. Chemotherapy can affect not only your immune system but also your overall recovery. If possible, scheduling the laser surgery during a period when your white blood cell count is expected to be higher (often a few days after chemotherapy) may be beneficial. Your healthcare team can help determine the optimal timing based on your treatment schedule and blood counts.

In summary, while laser surgery for retinal holes is generally safe, your current chemotherapy treatment and low white blood cell count introduce additional risks that must be carefully weighed. It is imperative to have a thorough discussion with both your oncologist and ophthalmologist to assess the risks and benefits of proceeding with the surgery at this time. They can provide personalized recommendations based on your specific health status and treatment plan. Always prioritize open communication with your healthcare providers to ensure that all aspects of your health are considered in the decision-making process.

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