Does steroid eye drops cause conjunctival vascular proliferation?
Hello Doctor: I recently underwent laser surgery for my myopia (TPRK) one month ago.
During my follow-up appointment one week after the procedure, I was prescribed a new eye drop (Flumetholone 0.1%).
I used it for about three days and started experiencing a stinging sensation in my eyes after each application.
After using the drops for about a week, I noticed that the blood vessels at the inner corner of my eyes, which were already present, had elongated, forming a C-shaped blood vessel when I pulled down my lower eyelid.
When I inquired at the clinic, they mentioned that this is unlikely to happen and suggested that I might have just become more aware of my eyes post-surgery.
Now, nearly two weeks later, the length of the blood vessel has not decreased.
I would like to ask the doctor if it is possible for vascular proliferation to occur suddenly within a week, or could the steroid eye drops be causing an increase in blood vessels? Thank you very much for taking the time to respond.
Miss Chen, 30~39 year old female. Ask Date: 2022/11/23
Dr. Gao Pilin reply Ophthalmology
Hello: Steroids do not increase the number of blood vessels, and vascular proliferation does not occur rapidly; it should have been present already.
Please rest assured.
Reply Date: 2022/11/23
More Info
Steroid eye drops, such as Flumetholone, are commonly prescribed for various ocular conditions due to their anti-inflammatory properties. However, concerns about their side effects, including conjunctival vascular proliferation, are valid and warrant a detailed discussion.
Firstly, it is essential to understand that steroid eye drops can lead to several ocular side effects, but the relationship between steroid use and conjunctival vascular proliferation is complex. While steroids are known to reduce inflammation and can be beneficial in managing conditions like allergic conjunctivitis or post-operative inflammation, they can also have adverse effects on the ocular surface. These include increased intraocular pressure, cataract formation, and potential changes in the conjunctival vasculature.
In your case, the observation of the conjunctival blood vessels becoming more prominent after starting the steroid eye drops raises a few considerations. It is not typical for steroid eye drops to cause a sudden increase in vascular proliferation within a week. Vascular changes, if they occur, usually develop over a more extended period and are often associated with chronic use rather than short-term application. The appearance of a C-shaped blood vessel could be due to pre-existing conditions or anatomical variations that have become more noticeable due to increased attention to the eye following surgery.
Moreover, the sensation of burning or discomfort after instilling the eye drops is not uncommon, especially in the initial days of treatment. This discomfort could be attributed to the formulation of the drops, the preservatives used, or even the underlying condition being treated. If the symptoms persist or worsen, it is advisable to consult your ophthalmologist for a thorough evaluation.
Regarding the possibility of vascular proliferation occurring rapidly, it is generally unlikely for significant conjunctival vascular changes to manifest within a week solely due to steroid use. If there is a concern about the appearance of new blood vessels, it may be worth considering other factors, such as the healing process post-surgery, the presence of inflammation, or even allergic reactions to the medication.
In conclusion, while steroid eye drops can influence conjunctival vasculature, significant changes typically do not occur rapidly. It is crucial to maintain open communication with your ophthalmologist, who can assess your specific situation, consider the possibility of alternative diagnoses, and adjust your treatment plan if necessary. If you continue to experience discomfort or notice changes in your ocular health, follow-up appointments are essential to ensure proper management and to address any concerns you may have regarding your recovery and the effects of the medications you are using.
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