Impact of Not Shaking Eye Suspensions Before Use - Ophthalmology

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Issues with ophthalmic suspensions?


Hello, doctor.
I would like to ask: If I forgot to shake the Winston Good Vision eye suspension 1 ml and directly instilled it into my eyes, will it cause any adverse effects on my eyes?

Xiao Ling, 30~39 year old female. Ask Date: 2022/11/23

Dr. Gao Pilin reply Ophthalmology


Hello: There will be no adverse effects; it just hasn't been mixed well, which may lead to reduced efficacy.
Please rest assured, there is no problem.

Reply Date: 2022/11/23

More Info


When it comes to using eye suspensions, such as the Winston eye suspension you mentioned, it is crucial to understand the importance of shaking the bottle before use. Eye suspensions contain active ingredients that are not fully dissolved in the solution; instead, they are suspended in a liquid medium. This means that the active components can settle at the bottom of the bottle if it is not shaken properly before use.

If you forget to shake the eye suspension and apply it directly to your eyes, the primary concern is that you may not receive the intended dosage of the active ingredient. The concentration of the medication may be uneven, leading to either an insufficient dose or, in some cases, a higher concentration of the active ingredient than intended. This could potentially affect the efficacy of the treatment, but it is unlikely to cause any immediate harm to your eyes.

In general, not shaking an eye suspension before use is not expected to result in significant adverse effects. However, the effectiveness of the medication may be compromised. For instance, if the active ingredient is concentrated at the bottom of the bottle, you might end up applying a solution that has a lower concentration of the medication, which may not adequately address your eye condition.

It is also worth noting that some eye medications can have specific side effects, and if you experience any discomfort, irritation, or unusual symptoms after using an eye suspension, it is advisable to consult with your eye care professional. They can provide guidance on how to properly use the medication and address any concerns you may have.

In summary, while forgetting to shake an eye suspension like the Winston eye suspension before use is not likely to cause serious harm, it can affect the medication's effectiveness. Always remember to shake the bottle well before applying the drops to ensure that you receive the correct dosage of the active ingredient. If you have any doubts or experience any adverse effects, do not hesitate to reach out to your healthcare provider for further advice.

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