Asymptomatic microscopic hematuria
Hello, doctor.
I do not smoke or drink alcohol.
During my health check this year, I found abnormalities in my urine test, including red blood cells, white blood cells, epithelial cells, urine casts, and leukocyte esterase, while other results were normal.
The findings were as follows: urine red blood cells: 3-5 (normal range: 0-2), urine white blood cells: 6-9 (normal range: 0-5), epithelial cells: 6-9 (normal range: 0-5), urine casts: 0-2 granular (negative), leukocyte esterase: +/- (negative).
I did not experience any pain or burning sensation during urination.
I have a vaginal Candida infection causing inflammation and mild cervical erosion.
I avoided menstruation during the urine test.
Additionally, I underwent an abdominal ultrasound, abdominal MRI, and endoscopic ultrasound (EUS), and my kidneys were normal.
Comparing with my health check from two years ago (2019), the urine red blood cells were also 3-5, but the normal range at that time was 0-5, so it was not reported as abnormal, and I did not pay attention to it.
The urine white blood cells were also abnormal two years ago.
I researched online and found that painless hematuria could indicate bladder cancer, so I would like to ask the doctor:
1.
What is my likelihood of having bladder cancer?
2.
Can urethritis be asymptomatic?
3.
Could vaginal inflammation and cervical erosion cause microscopic hematuria?
4.
If it unfortunately turns out to be bladder cancer, is microscopic hematuria generally present in the early stages? What is the early treatment success rate?
5.
How accurate is an ultrasound examination of the bladder? Should I undergo this test, or is it better to go directly for a cystoscopy?
6.
Does bladder cancer grow quickly?
7.
Since my urine red blood cells were also 3-5 two years ago, even though it was within the normal range of that health check center, is this still considered abnormal?
8.
If the hematuria is caused by bladder cancer, is it possible for it to remain unchanged for two years?
9.
Based on your experience, what could be the cause of my microscopic hematuria?
10.
What would you recommend as the next steps for me? Thank you.
Hoho, 30~39 year old female. Ask Date: 2022/11/26
Dr. Du Shixi reply Urology
Hello:
1.
Is my risk of bladder cancer high? --> Not very high.
2.
Can urinary tract infections be asymptomatic? --> Yes, it is possible.
3.
Can vaginitis and cervical erosion cause microscopic hematuria? --> If the urine specimen is collected correctly, this should not occur.
4.
If it unfortunately is bladder cancer, is microscopic hematuria generally present in the early stages? --> Yes, it is early, but hematuria is just a symptom; the likelihood of bladder cancer is still low.
Is the cure rate high in the early stages? --> Yes, early detection and treatment have a high cure rate.
5.
Is the accuracy of ultrasound examination of the bladder high? Should I undergo this, or is it better to go directly for cystoscopy? --> It depends on the physician's evaluation.
6.
Does bladder cancer grow quickly? --> It depends on the cell type.
7.
Two years ago, my urine showed 3-5 red blood cells, which is within the normal range for that health check center; does this still count as abnormal? --> Normal.
8.
Following up on that, if the hematuria is caused by bladder cancer, is it possible for it to remain unchanged for two years? --> A single urine test cannot determine this; multiple tests are needed before a physician suspects cancer.
9.
Based on the physician's experience, what could be the cause of my microscopic hematuria? --> There are many unknown causes.
10.
What would the physician recommend as the next step for me? --> Regular follow-up at the urology outpatient department, such as every six months; if there is visible hematuria, seek medical attention.
Thank you.
Reply Date: 2022/11/26
More Info
Asymptomatic microscopic hematuria, or the presence of red blood cells in the urine without accompanying symptoms, can be a concerning finding during routine health screenings. Your situation, with the presence of red blood cells, white blood cells, and epithelial cells in your urine, raises several important questions regarding potential causes and necessary follow-up actions.
1. Risk of Bladder Cancer: While the presence of microscopic hematuria can be associated with bladder cancer, it is important to note that the majority of cases of hematuria are not due to malignancy. The risk of bladder cancer increases with age, smoking history, and exposure to certain chemicals, but given your non-smoking status and relatively young age, the probability may be lower. However, it is crucial to rule out this possibility, especially since you have a history of abnormal urine findings.
2. Asymptomatic Urinary Tract Infections (UTIs): It is indeed possible to have a urinary tract infection without typical symptoms such as burning or pain during urination. Some individuals may experience mild or atypical symptoms, or none at all, particularly in cases of chronic or low-grade infections.
3. Inflammation from Vaginal and Cervical Conditions: Conditions such as vaginitis or cervical erosion can lead to inflammation that may potentially cause microscopic hematuria. However, these conditions typically do not directly cause blood in the urine unless there is significant inflammation or irritation that affects the urinary tract.
4. Early Detection of Bladder Cancer: If bladder cancer is present, it can manifest as microscopic hematuria, often in the early stages. Early-stage bladder cancer generally has a high cure rate, especially if detected early through appropriate diagnostic procedures.
5. Ultrasound Accuracy: Ultrasound is a useful tool for assessing the kidneys and bladder, but it may not always detect small tumors or early-stage bladder cancer. A cystoscopy, which involves direct visualization of the bladder, is often recommended for a definitive diagnosis if hematuria is present.
6. Growth Rate of Bladder Cancer: Bladder cancer can vary in growth rate. Some types are aggressive and can grow quickly, while others may be slow-growing. Regular monitoring and follow-up are essential to manage any potential malignancy.
7. Historical Urine Findings: The presence of red blood cells in your urine during previous tests, even if within the normal range, should not be overlooked. Consistent findings of hematuria warrant further investigation, especially if they persist over time.
8. Stability of Hematuria: It is possible for bladder cancer to remain stable for a period, but any persistent hematuria should be evaluated. Regular monitoring is crucial to detect any changes.
9. Possible Causes of Microscopic Hematuria: In your case, potential causes could include urinary tract infections, kidney stones, benign prostatic hyperplasia (in males), or even benign tumors. Given your history of inflammation, it may also be related to your gynecological conditions.
10. Next Steps: I would recommend discussing your findings with a urologist, who may suggest a cystoscopy to directly visualize the bladder and rule out any malignancies. Additionally, further urine tests, such as a urine cytology, may be beneficial. Regular follow-up and monitoring of your symptoms and urine findings are essential.
In summary, while the presence of microscopic hematuria can be concerning, it is important to approach the situation with a comprehensive evaluation. The likelihood of bladder cancer, while present, is not the only explanation for your findings. A thorough investigation by a healthcare professional will help clarify the cause and guide appropriate management.
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