Myocardial Perfusion Tests: Insights and Implications - Cardiology

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Myocardial perfusion imaging


Hello Doctor: I just completed an examination and have already had a stent placed.
This report was done because I moved and changed hospitals, and I am scheduled to review the report in about three weeks.
I would like to ask if there is a need for another stent based on the examination results.
I hope to understand the situation in advance.
Thank you for taking the time to respond!
Non-smoker, non-drinker.
Blood pressure: 110/70 mmHg; Pulse: 70 bpm; Physical examination: clear breath sounds, mild systolic heart murmur, mild leg edema.
Blood pressure: 137/71 mmHg; Pulse: 87 bpm; 111/11 UCG: RWMA (+), fair LVEF.
Image findings:
* Following the intravenous injection of 2 mCi of Tl-201 chloride after a standardized dipyridamole stress protocol (dipyridamole: 0.56 mg/kg, continuous IV infusion over 4 minutes; and aminophylline 50 mg slow IV push for relief of adverse reactions), post-stress and resting gated SPECT images of the heart were acquired using a gamma camera.
* SCINTIGRAPHIC FINDINGS:
(1) Mildly reversible perfusion defect at the apex and anterior wall.
(2) Mildly fixed perfusion defect at the inferior wall.
(3) Increased lung uptake in bilateral lung fields.
Lung/heart uptake ratio: Stress: 41%; Rest: 45%.
(4) The automated semiquantitative analysis of myocardial perfusion disclosed:
- Summed stress score (SSS): 10;
- Summed rest score (SRS): 0;
- Summed difference score (SDS): 10.
(5) Gated SPECT-estimated LVEF: Stress: 32%; Rest: 41%.
(6) Gated LV motion analysis disclosed no significant hypokinesia/dyskinesia.
The transient ischemic dilatation (TID ratio) of the LV was 1.07 (Normal < 1.1).
Impression & suggestion:
(1) Mild stress-induced ischemia at the apex and anterior wall is suspected.
* Camera-estimated extent of perfusion defect: 10%; reversibility ratio: 66%.
(2) Soft tissue attenuation is favored at the inferior wall.
(3) Impaired LV systolic function with stress-induced LV dysfunction is noted.

Miss Yi, 40~49 year old female. Ask Date: 2022/12/04

Dr. Wu Xueming reply Cardiology


The report indicates mild myocardial ischemia.
If the symptoms are mild, medication can be used for management, and regular outpatient follow-up is sufficient; cardiac catheterization is not necessarily required.

Reply Date: 2022/12/04

More Info


Understanding myocardial perfusion tests is crucial for assessing coronary artery disease (CAD) and determining the need for further interventions, such as stenting or coronary artery bypass grafting. Your recent myocardial perfusion scan results indicate some areas of concern, particularly regarding the perfusion defects observed in the apex and anterior wall of your heart. Let’s break down the findings and their implications.


Key Findings from Your Myocardial Perfusion Test
1. Reversible Perfusion Defects: The scan showed mildly reversible perfusion defects at the apex and anterior wall. This suggests that these areas of the heart are not receiving adequate blood flow during stress but may recover when the heart is at rest. This is indicative of ischemia, which is a condition where blood flow (and thus oxygen) is restricted to the heart muscle.

2. Fixed Perfusion Defect: The presence of a mildly fixed perfusion defect at the inferior wall indicates that there may be some permanent damage or scarring in that area, which does not improve with stress. This could be a result of previous ischemic events or myocardial infarction.

3. Lung Uptake: Increased lung uptake in the bilateral lung fields may suggest congestion or fluid overload, which can occur in heart failure or other cardiac conditions. The lung/heart uptake ratio is also a critical parameter, with values above normal indicating potential heart-related issues.

4. Left Ventricular Ejection Fraction (LVEF): Your estimated LVEF during stress was 32%, which is significantly low, indicating impaired systolic function. A normal LVEF is typically above 55%, and values below this threshold suggest that the heart is not pumping effectively, which could necessitate further evaluation and management.

5. Summed Stress Score (SSS): The SSS of 10 indicates a moderate level of ischemia, while the Summed Rest Score (SRS) of 0 suggests that there are no significant resting perfusion defects. The Summed Difference Score (SDS) of 10 reinforces the presence of stress-induced ischemia.


Implications for Further Management
Given these findings, the question of whether you need another stent or further intervention is a valid concern. Here are some considerations:
- Assessment of Ischemia Severity: The mildly reversible ischemia at the apex and anterior wall suggests that there may be areas of the heart that are at risk for further ischemic events. This could warrant closer monitoring and possibly intervention, especially if you have symptoms such as chest pain or shortness of breath.

- Evaluation of Fixed Defects: The fixed defect at the inferior wall may require further investigation to determine if it is due to previous myocardial infarction or other causes. If this area is significantly compromised, it may affect your overall cardiac function and could necessitate intervention.

- Heart Function: The low LVEF indicates that your heart's pumping ability is compromised. This is a critical factor in deciding on further interventions. If your heart function does not improve with medical management, or if you continue to experience symptoms, your cardiologist may recommend procedures such as angioplasty with stenting or even surgical options.

- Clinical Correlation: It is essential to correlate these findings with your clinical symptoms and other diagnostic tests, such as echocardiography and blood tests. Your cardiologist will consider your overall clinical picture, including risk factors like diabetes, hypertension, and family history, to make a comprehensive assessment.


Conclusion
In summary, while your myocardial perfusion scan indicates some areas of concern, the decision to proceed with further interventions like stenting will depend on a thorough evaluation by your cardiologist. It is crucial to discuss your symptoms, the implications of your test results, and potential treatment options during your upcoming appointment. Early intervention can be vital in preventing further complications, so maintaining open communication with your healthcare provider is essential.

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