Forearm Pain After IV Glucose Administration - Family Medicine

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Forearm pain


A few days ago, I received a glucose infusion at the hospital, and I experienced pain at the injection site.
The nursing staff explained that it was due to the hypertonic solution, but they quickly adjusted the flow rate, which gradually alleviated the pain.
However, today I noticed pain on the inner side of my arm, but there are no bruises or signs of trauma.
I'm unsure if this is related to the infusion.

Judy, 20~29 year old female. Ask Date: 2022/12/07

Dr. Xiao Yongxun reply Family Medicine


Dear Ms.
Judy:
1.
Common side effects or complications of intravenous therapy often arise from the infusion itself, the medications added, improper placement of the intravenous catheter, extravasation of the infusion from the venipuncture site, localized infections leading to cellulitis, and other factors.
Additionally, certain patient characteristics, improper movements, or concurrent use of specific medications can also lead to adverse medical events.
Since you have received a hypertonic glucose solution, infusing it too quickly can indeed cause localized discomfort.
However, aside from this reason, are there any other factors involved? I recommend that you return to the original hospital for a consultation, allowing the physician to examine you personally to minimize the risk of errors.

Reply Date: 2022/12/07

More Info


Forearm pain following intravenous (IV) glucose administration can be attributed to several factors, particularly when high-concentration solutions are involved. When a hypertonic solution, such as dextrose (glucose), is infused, it can cause irritation to the surrounding tissues and blood vessels. This irritation may lead to discomfort or pain at the site of infusion, which can sometimes radiate to nearby areas, such as the forearm.


Mechanisms of Pain After IV Glucose Administration
1. Hypertonicity: High-concentration glucose solutions are hypertonic, meaning they have a higher concentration of solutes compared to the surrounding tissues. When infused, they can draw water out of the cells, leading to cellular dehydration and irritation. This can cause localized pain and discomfort at the infusion site.

2. Chemical Irritation: The glucose solution can irritate the endothelial lining of the veins. This irritation can lead to inflammation, which may manifest as pain. The body’s inflammatory response can cause swelling and tenderness in the area.

3. Nerve Irritation: If the IV catheter is positioned near a nerve or if the infusion causes swelling that compresses nearby nerves, this can lead to pain or discomfort radiating along the arm.

4. Phlebitis: This is an inflammation of the vein that can occur after IV administration. Symptoms include pain, redness, and swelling along the vein. While you mentioned there are no visible bruises or swelling, it’s still possible to have a mild case of phlebitis that may not be immediately apparent.

5. Extravasation: If the glucose solution leaks out of the vein and into the surrounding tissue, it can cause significant pain and swelling. This is a more serious complication and typically presents with noticeable swelling and discoloration.


Recommendations
Given your symptoms of inner arm pain without bruising or swelling, it is advisable to monitor the situation closely. Here are some steps you can take:
- Rest the Arm: Avoid using the affected arm excessively to prevent further irritation.

- Apply a Cold Compress: If there is any swelling or discomfort, applying a cold compress can help reduce inflammation and numb the area.

- Pain Management: Over-the-counter pain relievers, such as ibuprofen or acetaminophen, can help alleviate discomfort if needed.

- Hydration: Ensure you are well-hydrated, as this can help your body recover from any irritation caused by the infusion.


When to Seek Medical Attention
If the pain persists, worsens, or if you develop additional symptoms such as swelling, redness, warmth at the site, or fever, it is important to seek medical attention. These could be signs of a more serious condition, such as phlebitis or an infection.

In conclusion, while it is common to experience some discomfort after IV glucose administration, persistent or severe pain should not be ignored. It is always best to consult with a healthcare professional if you have concerns about your symptoms. They can provide a thorough evaluation and determine if any further treatment is necessary.

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