Emergency Contraceptive Pills: FAQs and Insights - Obstetrics and Gynecology

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Emergency contraceptive pill


Hello Dr.
Chang, I have a few questions regarding contraceptive pills:
Q1: The mechanism of combined oral contraceptives is to trick the brain to prevent ovulation and inhibit the thickening of the endometrium.
In the absence of endometrial thickening, is the menstruation that occurs during the pill-free interval due to the shedding of the endometrium or is it a withdrawal bleed? If one engages in unprotected intercourse during the pill-free interval, does it increase the risk of endometriosis and infections?
Q2: The contraceptive pills available on the market are divided into 21 pills (e.g., YAZ) and 24+4 inactive pills (e.g., Alesse).
Why is there a difference in the number of active pills between the two? If I take Alesse (24+4) but only consume the 21 active pills, will the contraceptive efficacy be the same as taking YAZ (21 pills)?
Q3: If I am taking Alesse and I happen to go on a trip during the inactive pill phase, can I choose to take only the 21 active pills to induce an earlier menstruation? Or should I skip the 4 inactive pills and start the next pack directly to avoid menstruation? Thank you for your answers!

Xiao Lin, 20~29 year old female. Ask Date: 2022/12/16

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the components of contraceptive pills work by inhibiting ovulation to achieve contraceptive effects, and they can also suppress endometrial hyperplasia, making it more difficult for a fertilized egg to implant.
The withdrawal bleeding during the pill-free interval occurs due to hormone withdrawal.
It is best to complete all 24 pills in a 24+4 contraceptive regimen for more regular menstrual cycles.
If you need to delay your period, it is advisable to continue taking the next pack after finishing the 24 pills.
Thank you! Wishing you peace and health, Dr.
Chang.

Reply Date: 2022/12/16

More Info


Emergency contraceptive pills (ECPs) are a crucial aspect of reproductive health, providing women with a means to prevent unintended pregnancies after unprotected intercourse or contraceptive failure. Understanding how these pills work, their implications, and the nuances of their use can help women make informed choices about their reproductive health. Here, I will address your questions regarding ECPs, their mechanisms, and their usage.

Q1: Understanding Menstrual Changes While on ECPs
When taking hormonal contraceptives, including ECPs, the body undergoes changes that can affect the menstrual cycle. The primary mechanism of ECPs is to prevent ovulation, inhibit fertilization, and alter the endometrial lining to prevent implantation. If a woman experiences withdrawal bleeding during the placebo or inactive pill phase, this bleeding is typically due to the drop in hormone levels, leading to the shedding of the endometrial lining. This is often referred to as "withdrawal bleeding" and is not the same as a natural menstrual period.

Regarding the concern about endometriosis or infections due to unprotected intercourse during the inactive pill phase, it is essential to note that while the risk of endometriosis is not directly linked to the use of ECPs, engaging in unprotected intercourse can increase the risk of sexually transmitted infections (STIs). Therefore, using barrier methods, such as condoms, is advisable to reduce the risk of STIs, regardless of hormonal contraceptive use.

Q2: Differences in ECP Regimens
The difference in the number of active pills in various ECP regimens, such as the 21-pill regimen (e.g., "Yaz") versus the 24+4 regimen (e.g., "Alesse"), is primarily based on the formulation and intended use of the pills. The 24+4 regimen includes 24 active pills followed by 4 inactive pills, which can help maintain a more consistent hormone level and potentially reduce side effects.
If you choose to take only the 21 active pills from a 24+4 regimen, you may not achieve the same level of hormonal stability as with a full cycle. This could potentially affect the contraceptive efficacy, as the hormonal levels may not be sustained throughout the cycle. It is crucial to follow the prescribed regimen for optimal effectiveness.

Q3: Managing the Inactive Pill Phase
If you are considering skipping the inactive pills to avoid menstruation while traveling, it is generally acceptable to do so with most combined oral contraceptives. You can start a new pack immediately after finishing the active pills from the current pack, effectively skipping the placebo phase. However, this should be done with caution and ideally under the guidance of a healthcare provider, as it may lead to breakthrough bleeding or other side effects.

In summary, ECPs are a safe and effective method of preventing unintended pregnancies, but understanding their mechanisms and how to use them properly is essential. If you have further questions or concerns about your specific situation, it is always best to consult with a healthcare professional who can provide personalized advice based on your health history and needs.

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