Effective Treatments for Athlete's Foot and Nail Fungus: Expert Recommendations - Dermatology

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Please ask your questions regarding athlete's foot?


I was infected with athlete's foot while serving in the military, and I currently have onychomycosis (fungal nail infection).
I have seen a dermatologist who confirmed that I have both athlete's foot and onychomycosis.
Could you please recommend some safe and effective oral and topical medications for treatment? Additionally, could you inform me about the side effects of the recommended medications and any precautions I should take while using them? Due to my work commitments, I cannot frequently visit the hospital, so I would like to buy medications from a pharmacy, but I am concerned about purchasing harmful substances.
Thank you.

Xiao Zong, 20~29 year old female. Ask Date: 2003/11/05

Dr. Chen Yiying reply Dermatology


Hello: In response to your question, athlete's foot, commonly known as tinea pedis, has many topical medications that are available over the counter at pharmacies.
However, oral medications are prescription-only and have more significant side effects, so it is advisable to consult a physician at a hospital or clinic for a prescription.
Currently, the oral medication for onychomycosis (fungal nail infection) requires a treatment course of 12 weeks, and you can obtain a two-week supply at a time.
This can simultaneously treat both onychomycosis and athlete's foot.
Please make sure to see a physician and do not attempt to purchase oral medications from a pharmacy on your own.

Reply Date: 2003/11/05

More Info


When it comes to treating athlete's foot (tinea pedis) and nail fungus (onychomycosis), there are several effective options available, both oral and topical. It's essential to understand the nature of these fungal infections, as well as the medications that can help treat them effectively while minimizing side effects.


Oral Medications
1. Terbinafine (Lamisil): This is one of the most commonly prescribed oral antifungal medications for both athlete's foot and nail fungus. It is typically taken once daily for 6 to 12 weeks, depending on the severity of the infection. Terbinafine works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes.

Side Effects: Common side effects may include gastrointestinal disturbances (nausea, diarrhea), headache, and rash. Rarely, it can affect liver function, so liver function tests are recommended before and during treatment.

2. Itraconazole (Sporanox): This is another effective oral antifungal that can be used for nail fungus. It is usually taken in a pulse dosing regimen (e.g., 200 mg daily for one week, followed by three weeks off).

Side Effects: Similar to terbinafine, itraconazole can cause gastrointestinal issues and may affect liver enzymes. It is also contraindicated in patients with heart failure due to its potential to cause fluid retention.

3. Fluconazole (Diflucan): While not typically the first choice for nail fungus, fluconazole can be effective for certain types of fungal infections. It is often taken as a single dose or weekly for several weeks.

Side Effects: Fluconazole is generally well-tolerated, but it can cause headaches, gastrointestinal upset, and liver enzyme elevation. It is also important to monitor for potential drug interactions, especially if you are taking other medications.


Topical Treatments
1. Econazole: This is a topical antifungal cream that can be applied directly to the affected areas of athlete's foot. It is usually applied once or twice daily.

Side Effects: Topical treatments like econazole are generally well-tolerated, with minimal side effects, though some patients may experience local irritation or allergic reactions.

2. Terbinafine Cream: In addition to oral terbinafine, the topical cream can be effective for athlete's foot. It is applied once or twice daily for 1 to 2 weeks.

3. Clotrimazole or Miconazole: These are over-the-counter topical antifungals that can be used for athlete's foot. They are applied twice daily for several weeks.


Recommendations and Precautions
- Combination Therapy: For severe cases, a combination of oral and topical treatments may be more effective. However, this should be done under the guidance of a healthcare provider.


- Duration of Treatment: Fungal infections can take time to resolve, and it is crucial to complete the full course of treatment even if symptoms improve. Nail fungus, in particular, may take several months to fully clear as the nail grows out.

- Hygiene Practices: Maintaining good foot hygiene is essential. Keep your feet dry and clean, especially between the toes. Change socks regularly and wear breathable footwear to reduce moisture.

- Monitoring Side Effects: If you experience any unusual symptoms or side effects, such as jaundice (yellowing of the skin or eyes), severe abdominal pain, or persistent nausea, seek medical attention promptly.

- Consultation with a Healthcare Provider: While it is understandable that you may want to self-treat due to your work schedule, it is always best to consult with a healthcare provider before starting any new medication. They can provide personalized recommendations based on your medical history and the specifics of your condition.

In conclusion, effective treatment for athlete's foot and nail fungus involves a combination of oral and topical antifungal medications, along with good hygiene practices. Always be mindful of potential side effects and consult with a healthcare provider when in doubt.

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