Does Cholesterol Medication Affect Blood Test Results? Insights and Concerns

Q: Does Cholesterol Medication Affect Blood Test Results? Insights and Concerns

Hello Mr. <br>Hong： Coronary lipid-lowering agents may cause an increase in liver function tests, while changes in blood parameters are less common. <br>Since we are unaware of any other diseases or medications you may have, it is advisable to consult with your primary physician

Will treatment for hyperlipidemia affect blood test results?

1.
Last October, due to elevated cholesterol levels, my doctor recommended medication for hyperlipidemia (Rosuvastatin).
Recently, in two check-ups, my GPT levels have increased (currently at 61 IU/L), while my GOT is at 40 IU/L.
Is this normal? (Low-density lipoprotein cholesterol is 97 mg/dL).
2.
Over the past two years of blood tests, I have observed elevated neutrophils, low monocytes, and low lymphocytes.
Could this be related to the medication, or are there other issues I should be aware of? My white blood cell count is 9.27 (1000/uL), hemoglobin is 16 (g/dL), neutrophils are 81.4 (%), basophils are 0.5 (%), monocytes are 3.3 (%), red blood cell count is 5.45 (10^6/uL), hematocrit is 47.7 (%), total bilirubin is 1.27 (mg/dL), platelet count is 304 (1000/uL), and lymphocytes are 14 (%).

Mr. Hong, 40~49 year old female. Ask Date: 2022/12/29

Dr. Hou Angting reply Family Medicine

Hello Mr.
Hong: Coronary lipid-lowering agents may cause an increase in liver function tests, while changes in blood parameters are less common.
Since we are unaware of any other diseases or medications you may have, it is advisable to consult with your primary physician to evaluate whether a change in medication is necessary.
Wishing you good health.

Reply Date: 2022/12/29

More Info

Cholesterol medications, particularly statins like Rosuvastatin (冠脂妥), are commonly prescribed to manage elevated cholesterol levels and reduce the risk of cardiovascular diseases. However, they can have various effects on blood test results, particularly liver function tests and blood cell counts.
In your case, you mentioned that your recent blood tests showed elevated levels of GPT (alanine aminotransferase) at 61 IU/L and GOT (aspartate aminotransferase) at 40 IU/L. These enzymes are indicators of liver function, and their elevation can be a concern, especially in patients taking statins. Statins can sometimes lead to liver enzyme elevations, which may indicate liver stress or damage. While mild elevations are not uncommon and may not require discontinuation of the medication, it is crucial to monitor these levels closely. Your healthcare provider may recommend periodic liver function tests to ensure that the liver is tolerating the medication well.

Regarding your blood cell counts, you noted an increase in neutrophils, a decrease in monocytes, and a decrease in lymphocytes. Neutrophils are a type of white blood cell that plays a significant role in the immune response, particularly in fighting infections. An elevated neutrophil count can occur due to various reasons, including stress, infection, or inflammation. Conversely, low monocyte and lymphocyte counts can indicate different underlying conditions, including bone marrow suppression or chronic stress.

While it is possible that your cholesterol medication could influence these blood parameters, it is essential to consider other factors as well. For instance, infections, inflammation, or other medications can also affect blood cell counts. It is advisable to discuss these findings with your healthcare provider, who can evaluate your overall health status, consider your medication regimen, and determine if any adjustments are necessary.

In summary, cholesterol medications can indeed affect blood test results, particularly liver function tests and blood cell counts. It is essential to have open communication with your healthcare provider regarding any changes in your test results and to discuss the potential implications of your medications. Regular monitoring and follow-up can help ensure that any issues are addressed promptly, allowing for safe and effective management of your cholesterol levels and overall health.

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