Medication for Menstrual Irregularities: Your Questions Answered - Obstetrics and Gynecology

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I previously sought medical attention due to excessive menstrual bleeding and was prescribed hemostatic medication.
My menstrual period lasted from December 1 to December 13, during which I took Medrone (methylprednisolone) and Estrade (estradiol) from December 13 to December 19 for hemostasis and regulation.
After completing the medication, I was informed that my menstrual cycle would resume in a few days, and indeed, I had another period from December 21 to December 27, which I considered a new cycle.

However, during my follow-up appointment, I reported intermittent light bleeding, and the same medications, Medrone and Estrade, were prescribed again from December 27 to January 1.
Now, I am experiencing abdominal pain, nausea, and spotting.
Does this indicate that my period is about to start again? Why do they keep prescribing the same medications? Are these medications intended to induce menstruation or to suppress it?

Nì Mái, 30~39 year old female. Ask Date: 2023/01/04

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, December 21 should mark the start of a new menstrual cycle.
Starting medication on December 27 is likely aimed at regulating your menstrual cycle.
If there is no improvement, it is advisable to return to your original clinic for a follow-up.
Wishing you good health.

Reply Date: 2023/01/04

More Info


When it comes to managing menstrual irregularities, understanding the medications prescribed and their effects is crucial. In your case, you have been prescribed Medrone (a corticosteroid) and Estrade (an estrogen replacement therapy) to address heavy menstrual bleeding and to help regulate your menstrual cycle.
Medrone, which contains methylprednisolone, is often used to reduce inflammation and can have effects on the menstrual cycle. It is not typically used as a primary treatment for menstrual irregularities but may be prescribed in certain situations to manage symptoms or conditions that could be affecting your cycle. Estrade, on the other hand, is an estrogen medication that can help regulate the menstrual cycle and alleviate symptoms associated with hormonal imbalances.

The sequence of your menstrual cycles, along with the medications you have taken, suggests that your body is responding to the hormonal treatments. The fact that you experienced bleeding from December 21 to December 27 after taking the medications indicates that your body may be attempting to establish a more regular cycle. However, the subsequent light bleeding and abdominal pain you are experiencing could suggest that your body is still adjusting to the hormonal changes induced by the medications.

The medications you are taking can indeed influence your menstrual cycle, but they are not specifically designed to "induce" menstruation in the traditional sense. Instead, they aim to stabilize your hormonal levels, which can lead to a more regular cycle over time. The continuation of these medications may be due to your healthcare provider's assessment that your body needs more time to adjust, or they may be trying to manage any underlying conditions that could be contributing to your irregular bleeding.

As for the symptoms you are experiencing now—abdominal pain and light spotting—these could be indicative of several things. It is possible that your body is preparing for another menstrual cycle, especially if you have been experiencing irregularities. However, it is also important to consider that side effects from the medications can include gastrointestinal discomfort and changes in bleeding patterns.
If you are concerned about the ongoing symptoms, it is essential to communicate with your healthcare provider. They can provide clarity on whether the medications are working as intended or if adjustments are necessary. Additionally, they can help determine if the symptoms you are experiencing are typical side effects or if they warrant further investigation.

In summary, the medications you are taking—Medrone and Estrade—are intended to help manage your menstrual irregularities by stabilizing hormone levels. The ongoing light bleeding and abdominal pain could indicate that your body is still adjusting to these treatments. It is crucial to maintain open communication with your healthcare provider to ensure that your treatment plan is effective and to address any concerns you may have about your symptoms. Regular follow-ups and monitoring will help in managing your menstrual health effectively.

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