Do I Need to Stop Taking Pre-Pregnancy Medication After One Year? - Obstetrics and Gynecology

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Do I need to stop taking pre-exposure prophylaxis (PrEP) after one year?


Hello Doctor, I would like to ask about my current situation.
I have been taking PrEP for a year now, and tomorrow I will start my 13th pack.
So far, I have not experienced any side effects, and I do not have any plans for pregnancy in the future.
Do I still need to stop the medication for one month? If I do need to stop for a month, should I start taking PrEP again on the fifth day of my period or on the first day of my period? Thank you for your help!

Lin, 20~29 year old female. Ask Date: 2023/01/09

Dr. Chen Zhiyu reply Obstetrics and Gynecology


Hello! It is recommended to consult a gynecologist for evaluation before starting or stopping contraceptive pills.
Thank you!

Reply Date: 2023/01/09

More Info


When considering the use of pre-pregnancy medications, especially hormonal contraceptives like the one you mentioned (悅己事前藥), it is important to understand both the purpose of these medications and the implications of long-term use. Based on the information provided, you have been taking this medication for a year without experiencing significant side effects, and you do not have plans for pregnancy in the near future.
In general, hormonal contraceptives are designed to prevent ovulation and thus prevent pregnancy. If you are not planning to conceive, continuing to take the medication is a personal choice, but it is advisable to periodically reassess your need for it. The recommendation to stop taking hormonal contraceptives for a month before trying to conceive is primarily to allow your body to return to its natural hormonal cycle, which can help in assessing your fertility status and ensuring that your body is ready for a potential pregnancy.
However, since you mentioned that you do not have plans for pregnancy, there is no strict medical requirement for you to stop taking the medication after one year. If you choose to continue taking it, you can do so as long as you are comfortable and not experiencing adverse effects.
If you decide to stop taking the medication, it is generally recommended to allow your body some time to adjust. Stopping the medication for a month or more can help ensure that your menstrual cycle returns to its natural rhythm, which can be beneficial if you decide to conceive in the future. When you are ready to resume taking the medication, it is typically advised to start on the first day of your menstrual cycle. This is because starting on the first day helps to ensure that the medication is effective in preventing ovulation during that cycle.

It is also important to consult with a healthcare provider before making any changes to your medication regimen. They can provide personalized advice based on your health history and current situation. Regular check-ups can help monitor any potential side effects and ensure that the medication is still appropriate for your needs.

In summary, if you are not planning to conceive, you do not necessarily need to stop taking your pre-pregnancy medication after one year. However, if you do decide to stop, allowing a month for your body to adjust is a good practice. Always consult with your healthcare provider for tailored advice and to discuss any concerns you may have regarding your medication and reproductive health.

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