Tongue Base Cancer: Symptoms and Treatment Insights - Oncology

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Cancer Issues: Base of Tongue Cancer


My father has been battling cancer for nearly three months.
During the initial phase of chemotherapy, his condition was stable, and he was able to manage daily activities independently.
However, on January 25th, the day after completing radiation therapy, he suddenly became unable to stand on his own, started experiencing excessive sleepiness, and showed decreased responsiveness to external stimuli.
He has been snoring very loudly, unable to keep his legs flat, and has lost his appetite.
He has a significant history of smoking and drinking, as well as hypertension and diabetes.

Mr. Li, 30~39 year old female. Ask Date: 2023/01/27

Dr. Hu Ziren reply Oncology


During cancer treatment, if acute changes occur, it may be due to acute complications caused by the treatment (such as infections, dehydration, or hypercalcemia, etc.).
It is recommended to promptly take the patient to the emergency department for further management.

Reply Date: 2023/01/27

More Info


Tongue base cancer, also known as base of tongue squamous cell carcinoma, is a type of head and neck cancer that arises from the cells at the back of the tongue. This area is part of the oropharynx, which includes the soft palate, the base of the tongue, and the tonsils. Symptoms of tongue base cancer can vary but often include difficulty swallowing (dysphagia), pain in the throat or ear, a lump in the neck, changes in voice, and sometimes bleeding.
In your father's case, it appears that he has been undergoing treatment for tongue base cancer, which typically involves a combination of chemotherapy and radiation therapy, especially if the cancer is diagnosed at an advanced stage. The treatment aims to shrink the tumor, alleviate symptoms, and prevent the spread of cancer.
The sudden changes in your father's condition after completing radiation therapy, such as inability to stand, increased sleepiness, and decreased responsiveness, are concerning and may indicate complications related to his treatment. These could include:
1. Radiation Side Effects: Radiation therapy can lead to acute side effects such as fatigue, mucositis (inflammation of the mucous membranes), and difficulty swallowing. These side effects can significantly impact a patient's quality of life and ability to eat or drink.

2. Infection: Patients undergoing chemotherapy and radiation are at a higher risk for infections due to a weakened immune system. Symptoms such as increased sleepiness and difficulty standing could indicate an underlying infection that requires immediate medical attention.

3. Dehydration and Nutritional Deficiencies: If your father is unable to eat or drink properly, he may become dehydrated or malnourished, which can lead to further complications, including weakness and confusion.

4. Neurological Issues: The sudden inability to stand and changes in responsiveness could also suggest neurological issues, possibly related to the cancer itself or as a side effect of treatment.

Given your father's medical history of smoking, alcohol use, hypertension, and diabetes, these factors can complicate his overall health and response to cancer treatment. It is crucial to monitor these symptoms closely and seek immediate medical attention if they worsen or do not improve.
In terms of treatment insights, the management of tongue base cancer often involves a multidisciplinary approach, including oncologists, radiation therapists, and supportive care teams. If your father is experiencing significant side effects, it may be beneficial to discuss with his healthcare team about adjusting his treatment plan or providing supportive care measures to improve his quality of life.

In conclusion, tongue base cancer can present various symptoms and requires a comprehensive treatment approach. The sudden changes in your father's condition should be evaluated promptly by his medical team to address any potential complications and ensure he receives the appropriate care. Regular follow-ups and open communication with healthcare providers are essential in managing his health during this challenging time.

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