Please let me know your questions regarding the examination report?
Hello Dr.
Huang, I have been experiencing a persistent cough and often feel phlegm in my throat.
I have seen many doctors at various clinics and taken numerous medications without improvement.
Eventually, I went to a large hospital for further examination, and I have a question regarding the report that states, "Some remnant of thymus is noted." I translated this as: "Some remnants of the thymus are noted." Could this be a concerning sign? Do I need to follow up on this? I am also wondering if my long-term post-nasal drip could be causing my chronic cough symptoms.
I cough almost all day, feel phlegm in my airways, and when it gets severe, I experience wheezing during breathing.
It is particularly uncomfortable at night when lying down, making it difficult to sleep, and sometimes I cough so hard that my chest hurts.
About two years ago, I underwent surgery for a deviated septum, which resolved my nasal congestion, but my cough persists.
I have even been diagnosed with symptoms suggestive of empty nose syndrome.
CT report: Some remnant of thymus.
No active lung lesion.
A CT scan of the chest from the apex of the lung to the adrenal glands with contrast enhancement was performed, and the images revealed:
- No active lung lesion in both lungs.
- No significant mediastinal lymphadenopathy is noted.
- Some remnant of thymus is noted.
- Grossly normal appearance of bilateral adrenal glands.
- No osteolytic or osteoblastic bone lesion is identified in the visible bony structure.
X-ray report:
- Normal heart size.
- Clear bilateral costophrenic angles.
- Suggest clinical correlation and follow-up.
Standing chest PA view:
- The heart size is within normal limits.
- Apical pleural thickening on the right side.
Sputum report: The specimen submitted consists of more than 10 tissue fragments measuring up to 2.8 x 1.2 x 0.3 cm in size, fixed in formalin.
Grossly, they are tan to brown and soft to bony.
A representative section is taken.
Microscopically, it shows some fragments of cartilage tissue with focal degenerative changes and mild chronic inflammatory cell infiltration in the edematous stroma.
The overlying respiratory epithelium shows mild regenerative changes.
The vascular component shows congestion.
The overall picture is consistent with degeneration with a chronic inflammatory process.
Please correlate with clinical condition and follow up.
Feng, 30~39 year old female. Ask Date: 2023/01/30
Dr. Huang Yiwen reply Pulmonology
Dear Feng: The remnant of the thymus has no clinical significance.
Your symptoms are likely due to an allergic reaction, which includes all respiratory issues.
The chest pain is caused by chest tightness.
Changhua Hospital is concerned about you.
Reply Date: 2023/01/30
More Info
Understanding the implications of a report noting "some remnant of thymus" in the context of your chronic cough and overall health is essential. The thymus gland, located in the upper chest, plays a crucial role in the immune system, particularly during childhood and adolescence. It is responsible for the maturation of T-cells, which are vital for the adaptive immune response.
In adults, the thymus typically shrinks and is replaced by fatty tissue, which is a normal physiological process. The presence of a thymic remnant in an adult, especially if it is small and asymptomatic, is generally not a cause for concern. However, it is essential to correlate this finding with your symptoms and medical history. If the remnant is associated with any abnormalities or if there are other concerning symptoms, further evaluation may be warranted.
Your CT report indicates "no active lung lesion" and "no significant mediastinal lymphadenopathy," which suggests that there are no current infections or malignancies in the lungs or surrounding areas. This is a positive sign, indicating that your lungs are likely functioning well despite your chronic cough. However, the presence of chronic cough, especially with phlegm and wheezing, can be indicative of several underlying conditions, including chronic bronchitis, asthma, or post-nasal drip syndrome.
Given your history of long-term cough and the feeling of phlegm in your throat, it is plausible that your symptoms may be related to post-nasal drip, especially since you have a history of nasal issues. Post-nasal drip occurs when excess mucus accumulates in the back of the throat, often leading to coughing, throat irritation, and a sensation of mucus in the throat. This can be exacerbated by allergies, sinus infections, or structural issues in the nasal passages, such as those that may have persisted despite your previous surgery for a deviated septum.
The findings in your sputum analysis, which indicate chronic inflammation and degenerative changes, may suggest a long-standing inflammatory process in your airways. This could be due to chronic irritation from allergens, infections, or other environmental factors. It is crucial to address these underlying causes to alleviate your symptoms effectively.
In terms of follow-up, it would be advisable to consult with a pulmonologist or an ENT specialist who can provide a comprehensive evaluation of your respiratory symptoms. They may recommend further diagnostic tests, such as pulmonary function tests or a nasal endoscopy, to assess the condition of your airways and nasal passages more thoroughly.
Additionally, managing your symptoms may involve a combination of medications, including antihistamines for allergies, nasal corticosteroids to reduce inflammation, and bronchodilators if asthma is a concern. Lifestyle modifications, such as avoiding known allergens, staying hydrated, and using a humidifier, may also help alleviate your symptoms.
In summary, while the thymic remnant itself is likely not a cause for concern, your chronic cough and associated symptoms warrant further investigation to identify and treat any underlying conditions. A multidisciplinary approach involving both pulmonology and ENT specialists may provide the best pathway to relief and improved quality of life.
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