Can Pilocarpine Hydrochloride Help with Myopia Treatment? - Ophthalmology

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Can "Methacholine Methylsulfate" be used for myopia?

binghuan, 10~19 year old female. Ask Date: 2023/02/26

Dr. Gao Pilin reply Ophthalmology


Hello: "Neostigmine Methylsulfate" is a prescription medication primarily used to improve symptoms related to ocular muscle function.
According to current research, it appears to have limited effectiveness in the treatment of myopia and is not specifically indicated for myopia treatment.
However, individuals with myopia may use it to alleviate eye fatigue.

Reply Date: 2023/02/26

More Info


Pilocarpine Hydrochloride is primarily known as a medication used to treat conditions such as glaucoma and dry mouth. It works by stimulating the muscarinic receptors in the eye, leading to increased aqueous humor outflow and consequently lowering intraocular pressure. However, its role in treating myopia (nearsightedness) is not well established.

Myopia is a refractive error where distant objects appear blurry because the eye is either too long or the cornea has too much curvature. The treatment for myopia typically involves corrective lenses (glasses or contact lenses), refractive surgery (like LASIK), or orthokeratology (special contact lenses worn overnight to reshape the cornea).
There has been some research exploring the use of pilocarpine in the context of myopia control, particularly in children. Some studies suggest that low-dose pilocarpine may help slow the progression of myopia by inducing a slight increase in the depth of focus, which could potentially reduce the strain on the eye when focusing on near objects. However, these findings are still under investigation, and pilocarpine is not currently a standard treatment for myopia.

Regarding the mention of "新斯的明甲基硫酸鹽" (Physostigmine Methylsulfate), it is a different medication primarily used as an antidote for anticholinergic toxicity and for certain types of glaucoma. Like pilocarpine, it is not typically used for myopia treatment.
In summary, while there may be some emerging evidence regarding the use of pilocarpine in myopia control, it is not a conventional treatment for myopia. If you are considering treatment options for myopia, it is essential to consult with an eye care professional who can provide personalized advice based on your specific condition and needs. They can help determine the most effective and appropriate treatment options for managing myopia, considering the latest research and clinical guidelines.
In conclusion, while pilocarpine hydrochloride has its uses in ophthalmology, its application in myopia treatment is not well-supported by current evidence. Always consult with a healthcare provider before starting any new treatment.

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