Can I Take Alfluzosin 0.4mg and Cialis 5mg Together at Night? - Urology

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Can I take 0.4 mg of Livorel and 5 mg of Klonopin together before bedtime?


I have benign prostatic hyperplasia (BPH), which was assessed by ultrasound to be 34.
The doctor prescribed Alfuzosin 0.4 mg to improve my urinary condition, but I have been taking Cialis 5 mg daily to maintain erectile function.
Can I take these two medications together before bedtime?

A Zhe, 40~49 year old female. Ask Date: 2023/02/27

Dr. Li Xinyi reply Urology


There are no absolute contraindications; however, both medications can lower blood pressure.
It is advisable to monitor blood pressure and be aware of any dizziness or hypotension when changing body positions.

Reply Date: 2023/02/27

More Info


When considering the simultaneous use of Alfluzosin (0.4 mg) and Cialis (5 mg), it is important to understand the pharmacological properties of both medications and their potential interactions. Alfluzosin is an alpha-1 adrenergic antagonist primarily used to treat benign prostatic hyperplasia (BPH) by relaxing the muscles in the prostate and bladder neck, which helps improve urinary flow. Cialis, on the other hand, contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor that is commonly prescribed for erectile dysfunction and also has indications for BPH.

In general, it is considered safe to take Alfluzosin and Cialis together. However, there are some important considerations to keep in mind:
1. Blood Pressure Effects: Both medications can lower blood pressure, albeit through different mechanisms. Alfluzosin can cause orthostatic hypotension (a drop in blood pressure when standing up), and Cialis can also lead to a decrease in blood pressure. When taken together, there is a potential risk of additive hypotensive effects, which could lead to dizziness, lightheadedness, or fainting, especially when standing up quickly. It is advisable to monitor your blood pressure regularly and be cautious when changing positions.

2. Timing of Administration: While there is no specific contraindication to taking these medications together at night, it may be beneficial to space them out slightly to minimize any potential side effects. For example, you could take Alfluzosin first and then wait about 30 minutes before taking Cialis. This approach allows your body to adjust to the effects of Alfluzosin before introducing Cialis.

3. Consult Your Healthcare Provider: It is crucial to discuss any changes in your medication regimen with your healthcare provider. They can provide personalized advice based on your overall health, other medications you may be taking, and your specific medical history. Your doctor may also want to monitor you more closely when you start taking these medications together.

4. Potential Side Effects: Be aware of the common side effects associated with both medications. Alfluzosin may cause dizziness, fatigue, and nasal congestion, while Cialis can lead to headaches, flushing, and indigestion. If you experience any severe side effects or symptoms such as prolonged erections (priapism), chest pain, or severe dizziness, seek medical attention immediately.

5. Lifestyle Considerations: In addition to medication management, consider lifestyle changes that can help improve your symptoms related to BPH and erectile dysfunction. Maintaining a healthy diet, regular exercise, and avoiding excessive alcohol and tobacco use can have positive effects on both urinary function and erectile health.

In summary, taking Alfluzosin (0.4 mg) and Cialis (5 mg) together at night is generally safe, but it is essential to be aware of the potential for additive blood pressure effects and to monitor how you feel after taking them. Always consult with your healthcare provider for tailored advice and to ensure that your treatment plan is safe and effective for your specific situation.

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