Urinalysis shows protein in the urine, but blood tests indicate normal kidney function?
Hello, doctor.
Before the Lunar New Year, I went to a urology clinic for a urinalysis due to frequent urination, and it showed a slight presence of protein in my urine.
After the New Year, I went to Yonghe Cheng Hsin Hospital for blood and urine tests, and the doctor mentioned that my urine was a bit dilute, but all the results were normal.
Should I drink less water and retest? Additionally, I would like to ask if the non-steroidal anti-inflammatory drugs (NSAIDs) I took for a week and a half after undergoing a fistula surgery two weeks prior to my first urinalysis could affect the results?
Joey, 30~39 year old female. Ask Date: 2023/03/06
Dr. Du Shixi reply Urology
Hello: Proteinuria, aside from issues related to the kidneys' filtration function, is also related to diet.
Multiple urine tests are needed for accurate assessment.
Generally, if kidney function is normal, you can feel more at ease and schedule another urine test later (urology, nephrology) to identify the cause.
Wishing you good health.
Reply Date: 2023/03/06
More Info
Understanding urine protein levels and kidney function tests is crucial for assessing renal health. In your case, the presence of a small amount of urine protein during your initial test may raise some concerns, but it is important to interpret this result in the context of your overall health and any recent medical procedures or medications.
Firstly, urine protein levels can fluctuate based on various factors, including hydration status, physical activity, and even recent surgical procedures. Since you mentioned that you had undergone a fistula surgery two weeks prior to your first urine test and were taking non-steroidal anti-inflammatory drugs (NSAIDs) for pain management, these factors could potentially influence your urine protein levels. NSAIDs can sometimes affect kidney function, particularly in individuals with pre-existing kidney conditions or those who are dehydrated. However, in healthy individuals, short-term use of NSAIDs typically does not lead to significant renal impairment.
Regarding your second urine test, where the results were normal despite the urine being described as "a bit dilute," it is essential to understand that hydration can impact urine concentration. When you drink a lot of water, your urine becomes more diluted, which can lower the concentration of proteins and other substances. The key metric to assess proteinuria is the protein-to-creatinine ratio (PCR) or the albumin-to-creatinine ratio (ACR), as these ratios help normalize the protein levels based on urine concentration. If your protein levels are low relative to creatinine, it may indicate that the protein detected is not clinically significant.
In your case, if your urine protein was only slightly elevated during the first test and normal in the follow-up, it may not warrant immediate concern. However, if you continue to experience symptoms such as frequent urination or if there are any changes in your health, it would be prudent to follow up with your healthcare provider. They may recommend additional tests, such as a 24-hour urine collection for protein quantification, to get a more accurate assessment of your kidney function.
As for your question about whether you should drink less water before retesting, it is generally advisable to maintain a normal hydration level. Dehydration can lead to concentrated urine, which may artificially elevate protein levels. Instead, focus on drinking a consistent amount of water leading up to your test, as this will provide a more accurate representation of your kidney function.
In summary, while the presence of urine protein can be concerning, it is essential to interpret these results in the context of your overall health, recent medical history, and hydration status. If you have any ongoing concerns or symptoms, do not hesitate to consult your healthcare provider for further evaluation and guidance. Regular monitoring and communication with your doctor will help ensure that any potential issues are addressed promptly and effectively.
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