Corneal Neovascularization: Causes and Prevention Tips - Ophthalmology

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Corneal neovascularization


Hello, doctor: I would like to ask what to do if there are new blood vessels entering the cornea (as seen with a slit lamp) in the limbal area.
I wear contact lenses for about 8-10 hours a day.
My classmate, who has never worn contact lenses, also has corneal neovascularization, and it was observed with a slit lamp at 40x magnification that there are new blood vessels extending into the cornea throughout the limbal area.
What could be the cause of this? Both my classmate and I now have corneal neovascularization; how can we prevent the further formation of blood vessels? I heard from my teacher that corneal blood vessels cannot be treated with medication.
Additionally, if someone experiences dryness in their eyes and does not wear contact lenses, can they use contact lens lubricating drops as eye drops? Thank you, doctor, for your response.

boy, 10~19 year old female. Ask Date: 2003/11/27

Dr. Wang Yuwei reply Ophthalmology


1.
The cornea itself lacks blood vessels, and neovascularization occurs due to corneal hypoxia, with prolonged contact lens wear being the most common cause.
Your classmate's neovascularization is likely limited to the peripheral cornea; otherwise, they should see an ophthalmologist to rule out other underlying conditions.
As for you, it is advisable to reduce your contact lens wear to less than six hours a day to prevent worsening neovascularization.
Alternatively, switching to regular eyeglasses or rigid gas-permeable contact lenses can help alleviate corneal hypoxia.
2.
Dry eye syndrome is best treated with artificial tears prescribed by an ophthalmologist.
In your case, reducing contact lens wear can help alleviate the symptoms of dry eyes.

Reply Date: 2003/11/27

More Info


Corneal neovascularization, or the growth of new blood vessels into the cornea, can be a concerning condition that may affect vision and overall eye health. This process often occurs as a response to hypoxia (lack of oxygen) or inflammation in the cornea. In your case, the presence of neovascularization in the limbal region (the border between the cornea and the sclera) suggests that there may be underlying issues that need to be addressed.


Causes of Corneal Neovascularization
1. Hypoxia: One of the most common causes of corneal neovascularization is hypoxia, which can occur from prolonged contact lens wear. When the cornea does not receive enough oxygen, it can trigger the body to grow new blood vessels to supply oxygen to the affected area.

2. Inflammation: Conditions such as keratitis (inflammation of the cornea) can also lead to neovascularization. This inflammation can be caused by infections, allergies, or irritants.

3. Chronic Eye Conditions: Certain chronic conditions, such as dry eye syndrome or autoimmune diseases, can contribute to the development of neovascularization.

4. Trauma or Injury: Any trauma to the eye, including chemical burns or scratches, can lead to inflammation and subsequent neovascularization.

5. Systemic Conditions: Conditions like diabetes can also affect the health of the cornea and lead to neovascularization.


Prevention Tips
1. Limit Contact Lens Wear: If you are wearing contact lenses for 8-10 hours a day, consider reducing the duration or switching to a different type of lens that allows for better oxygen permeability. Daily disposable lenses may be a good option.

2. Regular Eye Exams: Schedule regular check-ups with an eye care professional to monitor the health of your cornea and detect any changes early.

3. Proper Lens Hygiene: Ensure that you are following proper hygiene practices when handling and cleaning your contact lenses to prevent infections that could lead to inflammation.

4. Use of Artificial Tears: If you experience dryness, using preservative-free artificial tears can help keep your eyes lubricated and reduce irritation. However, avoid using contact lens solutions as eye drops unless they are specifically designed for that purpose.

5. Avoid Eye Irritants: Protect your eyes from smoke, dust, and other irritants that could exacerbate inflammation.

6. Consult with an Eye Care Professional: If you notice any changes in your vision or if the neovascularization worsens, seek advice from an ophthalmologist. They may recommend treatments such as anti-inflammatory medications or other therapies to manage the condition.


Regarding Dry Eyes and Lubrication
If you are experiencing dry eyes but are not using contact lenses, it is generally safe to use lubricating eye drops (artificial tears) that are preservative-free. These drops can help alleviate dryness and discomfort. However, it is essential to choose products that are appropriate for your specific needs, and consulting with an eye care professional can provide personalized recommendations.


Conclusion
Corneal neovascularization is a condition that requires careful monitoring and management. By understanding the causes and implementing preventive measures, you can help protect your eye health. If you or your classmate are experiencing significant symptoms or changes in vision, it is crucial to consult with an eye care professional for a comprehensive evaluation and tailored treatment plan.

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