Missing One Antibiotic Pill: Should You Continue Treatment for Cellulitis? - Family Medicine

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I accidentally lost a dose of antibiotics?


On March 4th, I received treatment for cellulitis in the emergency department and was prescribed 250 mg of Dexa-Cillin, taking two pills every six hours for six days.
Since I was not fully recovered when the medication was nearly finished, I went to the infectious disease department on March 9th and received another seven days' worth of medication.
However, I accidentally lost one pill.
I currently feel that I am almost better.

1.
Will missing one pill have any impact?
2.
If I believe I have fully recovered, is it necessary to finish the seven days' worth of medication prescribed by the infectious disease department?
3.
I found online that the treatment duration for cellulitis is typically 7 to 10 days.
If I have already completed ten days of treatment and feel completely healed, do I need to finish the remaining three days of medication?

six four, 20~29 year old female. Ask Date: 2023/03/13

Dr. Lin Zhebin reply Family Medicine


Hello: 1.
Skipping a dose of antibiotics primarily affects the concentration of the medication in the body, which can impact the effectiveness of the treatment.
2.
It is recommended to complete the full course of antibiotics, as failing to eliminate all the bacteria may allow the surviving bacteria to develop resistance, potentially making future treatments more difficult.
3.
The treatment duration for cellulitis can actually extend up to 14 days, so it is advisable to finish the remaining 3 days of medication and then return for a follow-up appointment, where the physician can assess the infection status for greater peace of mind.

Reply Date: 2023/03/13

More Info


When it comes to antibiotic treatment, especially for conditions like cellulitis, adherence to the prescribed regimen is crucial for ensuring complete recovery and preventing antibiotic resistance. Let's break down your questions regarding the missed antibiotic pill and the overall treatment plan.

1. Impact of Missing One Pill: Missing a single dose of an antibiotic can potentially affect the overall concentration of the drug in your system, which is essential for effectively combating the infection. Antibiotics work by maintaining a certain level in the bloodstream to inhibit bacterial growth. If you miss a dose, it may lower the drug's effectiveness temporarily, but it does not necessarily mean that your treatment will fail. However, it is important to take the missed dose as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double up on doses.

2. Continuing Treatment After Feeling Better: Even if you feel significantly better, it is generally recommended to complete the full course of antibiotics as prescribed. This is because stopping treatment early can allow some bacteria to survive, which may lead to a resurgence of the infection. These surviving bacteria can also develop resistance to the antibiotic, making future infections harder to treat. Therefore, even if you feel well, it is advisable to finish the remaining days of your antibiotic course to ensure that all bacteria are eradicated.

3. Duration of Treatment for Cellulitis: The typical duration for treating cellulitis is indeed around 7 to 10 days, depending on the severity of the infection and the specific antibiotic used. If you have already completed ten days of treatment and feel completely healed, it may seem reasonable to stop taking the remaining pills. However, it is still best practice to finish the prescribed course unless directed otherwise by your healthcare provider. If you have any doubts, consult your doctor for personalized advice based on your specific situation.

In summary, while missing one pill may not drastically alter your treatment outcome, it is essential to adhere to the full course of antibiotics to prevent complications such as recurrence of the infection or the development of antibiotic-resistant bacteria. Always communicate with your healthcare provider about any concerns regarding your treatment plan, especially if you experience any side effects or have questions about your recovery. Your health and safety should always come first, and your doctor can provide the best guidance tailored to your individual needs.

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