Unexplained Pain in the Cheekbone Area - Neurology

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Pain on the left side?


Hello, doctor: May I ask why the pain is so severe when the zygomatic bone and masseter muscle are not swollen, there are no bruises, and anti-inflammatory medication has not been effective?

Awei, 30~39 year old female. Ask Date: 2023/03/17

Dr. Peng Shiwei reply Neurology


Hello, based on your symptoms, it is quite difficult to determine the issue.
I recommend that you visit a medical facility for further evaluation.
Thank you for your inquiry.

Reply Date: 2023/03/17

More Info


Understanding unexplained pain in the cheekbone area can be quite complex, especially when there are no visible signs of injury or inflammation. The pain you are experiencing could be attributed to several potential causes, and it is essential to consider both physical and neurological factors.

1. Temporomandibular Joint Disorder (TMJ): One of the most common causes of pain in the cheekbone area is related to the temporomandibular joint (TMJ). This joint connects the jawbone to the skull and can become inflamed or misaligned, leading to pain that radiates to the cheekbone. Symptoms may include jaw clicking, difficulty chewing, and headaches. TMJ disorders can be exacerbated by stress, teeth grinding (bruxism), or jaw clenching.

2. Nerve Pain: Another possibility is neuralgia, which is pain caused by irritation or damage to a nerve. The trigeminal nerve, which is responsible for sensation in the face, can sometimes become hypersensitive or inflamed, leading to sharp, shooting pains in the cheekbone area. This condition is known as trigeminal neuralgia and can occur without any visible signs of injury.

3. Sinusitis: Inflammation of the sinuses can also cause pain in the cheekbone area. Even if you do not have a cold or noticeable sinus symptoms, sinusitis can occur without typical signs. This can lead to pressure and pain in the facial region, particularly around the cheekbones.

4. Muscle Strain: The muscles around the jaw and face can become strained due to overuse or poor posture, especially if you spend long hours at a computer or clench your jaw. This muscle tension can lead to discomfort in the cheekbone area.

5. Dental Issues: Sometimes, dental problems such as an abscessed tooth or gum disease can cause referred pain to the cheekbone area. Even if there are no visible signs, underlying dental issues can manifest as facial pain.

6. Referred Pain: Pain can also be referred from other areas of the body. For example, issues with the neck or upper back can sometimes lead to discomfort in the facial region.
Given that anti-inflammatory medications have not provided relief, it may be beneficial to explore other treatment options. Here are some recommendations:
- Consult a Specialist: If you haven't already, consider seeing a dentist who specializes in TMJ disorders or a neurologist for nerve-related issues. They can provide a more thorough examination and may recommend imaging studies like an MRI or CT scan to rule out other conditions.

- Physical Therapy: Engaging in physical therapy can help address muscle tension and improve jaw alignment. A physical therapist can provide exercises to strengthen the jaw and neck muscles and improve posture.

- Stress Management: If stress is contributing to muscle tension or bruxism, consider stress management techniques such as mindfulness, yoga, or cognitive behavioral therapy.

- Alternative Therapies: Some patients find relief through acupuncture or chiropractic care, which can help with muscle tension and alignment issues.

- Pain Management: If the pain persists, a pain management specialist may be able to offer additional treatments, including nerve blocks or other interventions.

In summary, unexplained pain in the cheekbone area can arise from various sources, including TMJ disorders, nerve pain, sinusitis, muscle strain, dental issues, or referred pain. A comprehensive evaluation by a healthcare professional is essential to determine the underlying cause and appropriate treatment.

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