Oral Mucosal Folds: When to Seek Medical Advice - Internal Medicine

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Oral mucosal folds


The inner side of my lower lip feels strange when I lick it with my tongue.
After looking in the mirror, I noticed fine lines that appear like wrinkles or small fissures, aligned parallel to my teeth, but they do not extend to the sides.
I also feel that my lower lip is slightly swollen compared to before.
Aside from this, I have no discomfort.
However, before I noticed the fissures, I had a small clear blister on the inner side of my lower lip that disappeared after I woke up.
At the same time, I also developed a pimple on the outer side of my lower lip, but it is the type that is under the skin.
Do you think I need to see a doctor? Thank you.

Yan, 20~29 year old female. Ask Date: 2023/03/24

Dr. Hong Yuanbin reply Internal Medicine


Hello, regarding fine lines or unusual sensations, these are more subjective experiences and can be difficult to diagnose.
The blisters are suspected to be caused by the herpes simplex virus, which is often triggered by irregular sleep patterns or high stress levels.
Therefore, it is recommended to maintain a regular schedule and engage in moderate exercise.
If discomfort persists, you may consider consulting a dentist or an ear, nose, and throat specialist.
Thank you for your inquiry.

Reply Date: 2023/03/24

More Info


When it comes to oral mucosal folds and any changes in the oral cavity, it is essential to pay attention to the symptoms and their duration. Based on your description, you have noticed fine lines or folds on the inner side of your lower lip, which feel unusual when you touch them with your tongue. Additionally, you mentioned slight swelling of the lower lip and the presence of a small, transparent blister that resolved overnight, along with an internal pimple.
Firstly, it is important to understand that the oral mucosa can undergo various changes due to a multitude of factors, including trauma, irritation, infections, or even systemic conditions. The presence of fine lines or folds, especially if they are parallel to the direction of your teeth, could be a normal anatomical variation or a sign of irritation or inflammation. The transient blister you experienced could have been a minor mucosal lesion, which is not uncommon and often resolves on its own.

However, there are several reasons to consider seeking medical advice:
1. Duration and Persistence: If the fine lines or folds persist for more than a couple of weeks, or if they change in appearance, it would be wise to consult a healthcare professional. Persistent changes in the oral mucosa can sometimes indicate underlying conditions that may require further evaluation.

2. Associated Symptoms: While you currently do not have any discomfort, the presence of swelling and the history of a blister could suggest an inflammatory process. If you begin to experience pain, difficulty eating or swallowing, or any other concerning symptoms, it is advisable to seek medical attention.

3. Changes in Oral Hygiene: If you have recently changed your oral hygiene routine, such as using new dental products or experiencing increased stress, these factors can contribute to changes in the oral mucosa. A dental professional can help determine if your oral care routine is adequate or if adjustments are needed.

4. Potential Allergic Reactions: The internal pimple you described could be related to an allergic reaction or irritation from food, dental products, or other environmental factors. If you suspect this might be the case, discussing it with a healthcare provider can help identify the cause.

5. Underlying Health Conditions: Given your concerns about the changes in your oral mucosa, it may be beneficial to consider any systemic health issues that could be contributing. Conditions such as autoimmune diseases, vitamin deficiencies, or hormonal changes can manifest in the oral cavity.

In conclusion, while the symptoms you describe may not seem alarming at this moment, it is always better to err on the side of caution when it comes to changes in the oral cavity. If the fine lines or swelling persist, or if you develop any new symptoms, I recommend scheduling an appointment with a dentist or an oral health specialist. They can perform a thorough examination, possibly including diagnostic imaging or biopsies if necessary, to rule out any serious conditions and provide appropriate treatment or reassurance. Remember, early intervention is key to managing any potential oral health issues effectively.

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