Do Atropine Eye Drops Increase Risk of Eye Diseases? - Ophthalmology

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Do mydriatic agents cause eye diseases?


Hello, doctor.
Last December, after my ophthalmology appointment, I have been intermittently using atropine 0.5% eye drops as instructed by my doctor.
However, I have the following concerns: (I am also taking lutein supplements) 1.
Does the use of atropine eye drops significantly increase the risk of macular degeneration or cataracts? 2.
Can atropine eye drops cause elevated intraocular pressure, and how can I lower my eye pressure if it does? 3.
Until what age is it recommended to continue using atropine eye drops? (I am currently 17 years old, and my prescription is still changing rapidly while using the drops.) 4.
Are the photochromic prescription glasses provided by the optical shop sufficient for UV protection during the use of atropine eye drops and daily activities? 5.
I had atropine drops in middle school but did not take proper precautions for UV protection at that time.
Will this cause any issues in the future? (It has been 3 years since then, and my eye condition is currently normal.) Thank you for your responses!

KB, 10~19 year old female. Ask Date: 2023/03/26

Dr. Gao Pilin reply Ophthalmology


Hello: 1.
The relationship between the use of dilating drops and the increased risk of macular degeneration or cataracts remains controversial.
Some studies suggest that long-term use of dilating agents may be associated with an increased risk of macular degeneration and cataracts; however, the results of these studies are not consistent.
Therefore, the decision to use dilating drops should be evaluated and recommended by your physician based on your individual circumstances.
2.
Dilating drops may temporarily increase intraocular pressure, but this effect is usually transient and does not last long.
If you are at risk for elevated intraocular pressure, you should inform your physician before using dilating agents.
Methods to lower intraocular pressure include the use of pressure-lowering medications, maintaining appropriate exercise, and controlling weight.
3.
The duration of dilating drop use should be assessed and recommended by your physician based on your individual situation.
Generally, the frequency of dilating agent use decreases after adulthood; however, if your refractive error is changing rapidly, more frequent use of dilating drops may be necessary to monitor vision changes.
4.
In general, photochromic prescription glasses can be used with dilating drops or for daily UV protection.
However, since dilating drops cause pupil dilation, it is important to note that after using dilating drops, you may need higher UV protection, such as wearing sunglasses.
5.
Long-term use of dilating drops may increase the risk of eye diseases, but whether this is a concern depends on individual circumstances.
If your current eye condition is normal, there may be no need for excessive worry.
However, to protect your eyes, it is recommended to use UV protection measures, such as wearing sunglasses or hats, to reduce the time your eyes are exposed to UV light.
Additionally, it is advisable to have regular eye examinations and to follow your physician's recommendations.

Reply Date: 2023/03/26

More Info


Atropine eye drops are commonly used in the treatment of myopia (nearsightedness) and for various diagnostic purposes, such as dilating the pupils during eye examinations. While atropine can be beneficial, it is important to understand its potential side effects and implications for eye health, especially in young patients like yourself.

1. Risk of Eye Diseases: There is no strong evidence to suggest that the use of atropine eye drops significantly increases the risk of macular degeneration or cataracts. However, prolonged use of any medication should be monitored by an eye care professional. Atropine works by relaxing the ciliary muscle of the eye, which can help in controlling the progression of myopia, but it does not inherently cause degenerative changes in the retina or lens. Regular eye examinations are crucial to monitor any changes in your eye health.

2. Intraocular Pressure (IOP): Atropine can cause a temporary increase in intraocular pressure in some individuals, particularly those who may have a predisposition to glaucoma. If you have a history of elevated eye pressure or glaucoma in your family, it is essential to discuss this with your eye doctor. If you experience symptoms such as headaches, blurred vision, or eye pain, you should seek medical attention promptly. To manage eye pressure, your doctor may recommend specific medications or lifestyle changes, such as reducing caffeine intake, maintaining a healthy weight, and staying hydrated.

3. Duration of Use: The decision on how long to continue using atropine drops should be made in consultation with your eye care provider. In many cases, atropine is used until the myopia stabilizes, which can vary from person to person. Some practitioners recommend tapering off the medication in late adolescence or early adulthood, but this should be tailored to your individual needs and eye health status.

4. UV Protection: Regarding your question about photochromic lenses, they can provide adequate UV protection when using atropine eye drops. However, it is essential to ensure that the lenses are rated for UV protection and that they darken sufficiently in bright light. Wearing sunglasses with UV protection when outdoors is also advisable, especially since atropine can cause light sensitivity due to pupil dilation.

5. Past Use of Atropine: If you used atropine in the past without proper UV protection, it is understandable to be concerned. However, the eyes are resilient, and if you have not experienced any adverse effects or symptoms since then, it is likely that your eyes have not sustained significant damage. It is always a good practice to have regular eye check-ups to ensure that your eyes remain healthy.

In summary, while atropine eye drops are generally safe and effective for managing myopia, it is crucial to use them under the guidance of an eye care professional. Regular monitoring of your eye health, awareness of any side effects, and protective measures against UV exposure are essential components of your eye care regimen. If you have any further concerns or experience any unusual symptoms, do not hesitate to reach out to your eye doctor for personalized advice and care.

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