Key Questions About Cancer Risks and Diagnosis in Oncology - Oncology

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Some questions I would like to confirm?


Hello, Doctor.
I have health anxiety and often think about many things.
I hope you can provide clear answers to my questions:
1.
How closely should I monitor my health if a relative has had cancer? My grandmother had stomach cancer; should I be particularly cautious?
2.
How many years does it typically take for stomach cancer to develop?
3.
If I had an endoscopy last month with no abnormalities, is it possible for issues to suddenly appear in a short time?
4.
Can diseases like gastric ulcers turn into cancer? I’ve seen claims online about this, and I’m unsure if they are true.
5.
What is the probability of someone my age developing stomach cancer?
6.
Does secondhand smoke and cooking fumes from a distance pose a cancer risk? If I only smell it briefly, is there any danger?
7.
How reliable is the endoscopy procedure?
Thank you very much for your answers, Doctor.

Mr. Chen, 20~29 year old female. Ask Date: 2023/04/20

Dr. Hu Ziren reply Oncology


1.
Only less than 2% of stomach cancer is hereditary; however, the causes of cancer require several conditions: 1.
personal factors (such as smoking and alcohol consumption), 2.
environmental factors, and 3.
genetic mutations.
Therefore, even if there are hereditary factors, the risk of developing cancer will be very low without environmental and personal factors.
2.
There is no definitive conclusion.
3.
No, but if concerned, consider having an upper endoscopy every 1-2 years.
4.
Recurrent gastric ulcers can lead to cancer.
5.
There is no definitive conclusion.
6.
Yes, but the risk is very low.
7.
There is a very high sensitivity to early lesions in the stomach; if there are any questions related to endoscopy, it is recommended to consult a gastroenterologist.

Reply Date: 2023/04/20

More Info


When it comes to cancer risks and diagnosis, there are several important factors to consider, especially for individuals with a family history of cancer. Here’s a comprehensive overview addressing your key questions:
1. Family History and Cancer Risk: Having a family member with cancer can indeed increase your risk, particularly if they are first-degree relatives (parents, siblings, children). In your case, since your grandmother had stomach cancer, it’s wise to be vigilant, but it doesn’t necessarily mean you will develop cancer. The risk is influenced by genetic factors, lifestyle, and environmental exposures. Regular screenings and consultations with a healthcare provider can help manage this risk.

2. Development of Stomach Cancer: Stomach cancer, like many cancers, typically develops over several years. It often starts with precancerous conditions such as chronic gastritis or gastric ulcers. While the exact timeline can vary, it can take a decade or more for stomach cancer to develop from these conditions. Factors such as diet, smoking, and Helicobacter pylori infection can accelerate this process.

3. Sudden Changes Post-Endoscopy: If you had an endoscopy last month that showed no abnormalities, it is unlikely that a significant issue would develop within such a short time frame. However, some conditions can progress rapidly, so if you experience new symptoms (like persistent pain, weight loss, or changes in appetite), it’s essential to follow up with your healthcare provider.

4. Gastric Ulcers and Cancer Risk: Gastric ulcers can potentially lead to stomach cancer, particularly if they are chronic and associated with H. pylori infection. While not all ulcers will progress to cancer, it’s crucial to manage them properly and monitor any changes. Regular check-ups and adherence to treatment plans can help mitigate this risk.

5. Cancer Incidence by Age: The probability of developing cancer increases with age. For someone in their 30s, the risk is relatively low compared to older age groups. However, lifestyle factors (like smoking, diet, and exercise) and family history can influence this risk. It’s advisable to discuss your specific risk factors with a healthcare provider who can provide personalized advice.

6. Secondhand Smoke and Carcinogens: Exposure to secondhand smoke and pollutants like cooking fumes can increase cancer risk, but the risk is generally associated with long-term exposure rather than brief encounters. Occasional exposure is unlikely to cause significant harm, but it’s best to minimize exposure whenever possible.

7. Reliability of Endoscopy: Endoscopy is a highly reliable diagnostic tool for detecting abnormalities in the gastrointestinal tract, including precancerous lesions and cancers. While no test is perfect, endoscopy has a high sensitivity for detecting gastric cancer, especially when performed by an experienced gastroenterologist. If you have concerns about the results, discussing them with your doctor can provide clarity.

In summary, while family history and certain health conditions can increase cancer risk, regular screenings, a healthy lifestyle, and open communication with healthcare providers are essential for early detection and prevention. If you have specific concerns or symptoms, do not hesitate to seek medical advice. Regular check-ups and being proactive about your health can significantly impact your overall well-being and cancer risk management.

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