Breast Tumor Biopsy Results: What You Need to Know - Surgery

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Breast tumor biopsy issues?


Hello Doctor, I am 27 years old and have no family history of breast cancer.
Last week, I went for a breast surgery consultation and found a 1 cm tumor.
The doctor suggested a biopsy and believed the likelihood of malignancy was low, so it was a precautionary measure.
The biopsy results came back benign, but the doctor recommended removal, explaining that there were signs of squamous metaplasia.
I have since scheduled minimally invasive surgery to remove the tumor for further testing.
I would like to ask if the presence of squamous metaplasia is very concerning.
Since the biopsy results were benign, will the pathology results from the tumor removal be the same? Although the doctor mentioned that the chances of a reversal are very small, I am still worried about the possibility of the results being overturned.
Thank you, Doctor.

Miss Huang, 20~29 year old female. Ask Date: 2023/04/29

Dr. Chen Jiaming reply Surgery


The biopsy results of the breast tumor show squamous metaplasia.
The clinician recommends complete excision of the tumor due to concerns that it may be metaplastic squamous cell carcinoma (SCC).
Generally, the likelihood of such malignant tumors occurring in the breast is very low, as SCC is more commonly found in the skin, respiratory tract, and upper gastrointestinal tract.
However, regardless of how small the chance is, if it arises, it must be addressed with another surgery (minimally invasive surgery is not suitable for tumors suspected to be cancerous), along with potential subsequent chemotherapy.
Instead of worrying excessively, it would be better to wait for the final pathological results.

Reply Date: 2023/04/29

More Info


Understanding breast tumor biopsy results can be a source of anxiety, especially when faced with terms like "squamous metaplasia" and recommendations for further procedures. In your case, the initial biopsy indicated a benign lesion, which is a positive outcome. However, the presence of squamous metaplasia raises some questions that are worth exploring.


What is Squamous Metaplasia?
Squamous metaplasia refers to a process where one type of cell transforms into another type, specifically, epithelial cells changing into squamous cells. This can occur in various tissues, including breast tissue. While squamous metaplasia itself is not cancerous, it can be associated with certain conditions that may warrant closer monitoring. In the breast, it can sometimes be a response to chronic irritation or inflammation.


Implications of Your Biopsy Results
1. Benign vs. Malignant: The fact that your biopsy results came back benign is reassuring. Benign lesions are non-cancerous and typically do not pose a threat to your health. However, the recommendation for surgical removal suggests that your healthcare provider wants to ensure that there are no underlying issues that could develop into something more serious in the future.

2. Risk of "Flipping" to Malignancy: While your doctor mentioned that the likelihood of the biopsy results being overturned is very low, it is understandable to feel concerned. The presence of squamous metaplasia does not inherently mean that there is a high risk of cancer. It is more about the need for careful evaluation to rule out any potential precursors to malignancy.

3. Further Testing: The upcoming minimally invasive surgery to remove the tumor will allow for a more comprehensive examination of the tissue. This is crucial because the initial biopsy may not capture the entire lesion, and further analysis can provide more definitive information about the nature of the cells involved.


What to Expect After Surgery
- Pathology Report: After the tumor is removed, it will be sent for pathological examination. This report will provide detailed information about the tumor's characteristics, including whether there are any signs of malignancy. Given that your initial biopsy was benign, there is a strong chance that the results will remain consistent, but it is essential to await the final report.

- Follow-Up Care: Depending on the results of the pathology report, your doctor will discuss the next steps. If the results confirm benign findings, you may simply need regular follow-ups. If there are any concerning features, your doctor will outline a management plan, which may include further treatment or monitoring.


Conclusion
In summary, while the presence of squamous metaplasia can be concerning, it does not automatically indicate a high risk of cancer. Your initial benign biopsy result is a positive sign, and the upcoming surgery will provide more clarity. It is essential to maintain open communication with your healthcare provider, express your concerns, and ask questions about any aspects of your care that you do not understand. Remember, early detection and proactive management are key components of breast health, and you are taking the right steps by following through with your doctor's recommendations.

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