Assessing Severity: Your Joint Pain and Treatment Options - Internal Medicine

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Mild or severe?


Mild or severe? Celebrex (celecoxib) 200 mg, taken once in the morning and once in the evening, has become ineffective.
Currently, I am experiencing pain in my knee joints, temporomandibular joints, finger joints, and both shoulder joints.
I have difficulty squatting and getting up from my knees, and I feel like I am racing against a wheelchair—it's really terrible.
During my follow-up visit, the doctor prescribed Salazine (sulfasalazine) 500 mg, to be taken once in the morning and once in the evening.
The doctor also ordered blood tests to check for autoimmune disorders, biochemical immune viruses, and other biochemical tests.
Additionally, I received a follow-up appointment slip, and I am supposed to return in 28 days to review the blood test results.
Why is it 28 days? Has the doctor given up on me?

felix, 70~79 year old female. Ask Date: 2023/05/07

Dr. Zeng Guosen reply Internal Medicine


There are many differential diagnoses for joint pain.
If the symptoms persist and the response to medication is poor, it is advisable to return for a follow-up appointment sooner rather than waiting for 28 days.
Thank you.

Reply Date: 2023/05/07

More Info


Based on your description, it seems that you are experiencing significant joint pain affecting multiple areas, including your knees, jaw, fingers, and shoulders. You mentioned that you have difficulty squatting and standing up, and you are even using a wheelchair at times. This situation can be quite distressing, and it’s understandable that you are seeking clarity regarding the severity of your condition and the treatment options available.

From a medical perspective, the symptoms you are experiencing could be indicative of a systemic issue, possibly related to autoimmune disorders or inflammatory conditions. The medications you have been prescribed, such as Celebrex (celecoxib) and Salazine (sulfasalazine), are commonly used to manage pain and inflammation associated with conditions like rheumatoid arthritis or other inflammatory arthritis. Celebrex is a non-steroidal anti-inflammatory drug (NSAID) that helps reduce pain and inflammation, while Salazine is often used to treat inflammatory bowel disease and rheumatoid arthritis.

The fact that you are experiencing persistent pain despite taking these medications suggests that your condition may require further evaluation. The blood tests your doctor has ordered, including tests for autoimmune markers and biochemical assessments, are essential for diagnosing underlying conditions that could be contributing to your joint pain. Autoimmune diseases can sometimes take time to diagnose, as they often require a combination of clinical evaluation and laboratory tests to confirm.

Regarding the 28-day follow-up period, this timeframe is not unusual in medical practice. It allows sufficient time for the laboratory to process the tests and for your doctor to review the results comprehensively. It’s important to understand that your doctor is not giving up on you; rather, they are taking a systematic approach to identify the root cause of your symptoms. This process can be frustrating, especially when you are in pain, but it is crucial for developing an effective treatment plan.

In the meantime, here are some recommendations that may help manage your symptoms:
1. Physical Therapy: Engaging in physical therapy can help improve your joint function and reduce pain. A physical therapist can design a personalized exercise program that focuses on strengthening the muscles around your joints, improving flexibility, and enhancing overall mobility.

2. Pain Management: If your current medications are not providing adequate relief, discuss this with your doctor. They may consider adjusting your medication regimen or adding adjunct therapies, such as corticosteroids or other immunosuppressive agents, depending on your diagnosis.

3. Lifestyle Modifications: Incorporating low-impact exercises, such as swimming or cycling, can help maintain joint mobility without putting excessive strain on them. Additionally, maintaining a healthy weight can reduce stress on weight-bearing joints like the knees.

4. Dietary Considerations: Some patients find relief from joint pain by adopting an anti-inflammatory diet, which includes foods rich in omega-3 fatty acids (like fish), fruits, vegetables, and whole grains while avoiding processed foods and sugars.

5. Regular Follow-ups: Keep your follow-up appointments and communicate openly with your healthcare provider about any changes in your symptoms or concerns you may have.

In summary, while your symptoms may seem severe, it is essential to work closely with your healthcare team to identify the underlying cause and develop a comprehensive treatment plan. Patience is key, as the diagnostic process can take time, but with the right approach, there is hope for improvement in your condition.

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