How Long Does It Take for Antibiotics to Control an Infected Cyst? - Dermatology

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How long does it take for medication to control an inflamed sebaceous cyst?


Hello Doctor: I have a sebaceous cyst on the back of my neck that has been present for about 3.4 years.
Recently, it suddenly became larger and painful, and I even noticed a little pus coming out.
The next day, I immediately went to see a dermatologist who prescribed me antibiotics and an ointment.
They applied the medication at that time, but they couldn't extract any pus during the visit.
I have been taking the medication on schedule without missing any doses, but after two days, the pain has actually increased (it hurts even without touching it), and there is some swelling and tenderness in the surrounding area as well.
Is this situation normal? How many days of medication should I take before the inflammation subsides? Additionally, can I use povidone-iodine to clean the wound when changing the dressing myself? Thank you, Doctor.

Vic, 20~29 year old female. Ask Date: 2023/05/10

Dr. Li Yufen reply Dermatology


Hello: The severity of a ruptured cyst with inflammation can vary greatly in clinical practice.
If symptoms such as redness, swelling, heat, and pain become increasingly pronounced, it is advisable to return for follow-up treatment sooner.
During dressing changes, you can use povidone-iodine to clean the wound, followed by applying an ointment.
If the skin condition does not improve or worsens, it is recommended to consult a nearby dermatologist for diagnosis and treatment.
Thank you!

Reply Date: 2023/05/10

More Info


When dealing with an infected cyst, the duration of antibiotic treatment can vary based on several factors, including the severity of the infection, the type of bacteria involved, and the individual’s overall health. In your case, it sounds like you have a sebaceous cyst that has become infected, which can lead to symptoms such as pain, swelling, and the presence of pus.

Typically, antibiotics are prescribed to help control the infection and prevent it from spreading. The standard recommendation for antibiotic therapy in cases of skin infections, including infected cysts, is usually around 5 to 10 days. However, if you are experiencing increased pain and swelling after two days of antibiotic treatment, it may indicate that the infection is not responding as expected, or that there may be other underlying issues at play.

It is important to note that antibiotics may take some time to show significant improvement, but if you are not noticing any relief or if your symptoms are worsening, it is crucial to follow up with your healthcare provider. They may need to reassess your condition, possibly perform a drainage procedure if there is significant pus accumulation, or consider a different antibiotic if there is a concern about antibiotic resistance or if the bacteria involved are not susceptible to the prescribed medication.

Regarding your question about using iodine (such as Betadine) to clean the wound, it is generally acceptable to use an antiseptic solution to clean the area around the cyst. However, it is essential to avoid using harsh chemicals directly on the wound unless advised by your healthcare provider. Instead, gently cleaning the area with mild soap and water is often sufficient. If you have been prescribed a topical antibiotic ointment, you should apply that as directed after cleaning.

In summary, while antibiotics are an essential part of treating an infected cyst, the duration and effectiveness can vary. If you are experiencing worsening symptoms, it is vital to consult your healthcare provider for further evaluation and management. They may need to adjust your treatment plan to ensure proper healing and to address any complications that may arise from the infection. Always follow your healthcare provider's instructions regarding medication and wound care to promote optimal recovery.

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