Missed Period: Delays and Pregnancy Concerns - Obstetrics and Gynecology

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Missed menstruation?


Hello Doctor, I would like to inquire about my menstrual period that was originally due on April 22, which is now 20 days late according to my app.
However, my boyfriend and I have not had sexual intercourse in the past few months, only some manual stimulation.
Feeling uneasy, I took a pregnancy test 18 days after my missed period, and it showed one line.
Can I be certain that there is no possibility of pregnancy? Last month, I had an inflammation of the tonsils and took medication; could this have affected the timing of my menstrual cycle and ovulation? Thank you, Doctor.

Wang Xiaomei, 20~29 year old female. Ask Date: 2023/05/12

Dr. Huang Yuande reply Obstetrics and Gynecology


If there is no sexual intercourse, pregnancy should not occur.
Generally, illness or stressful environments can affect the menstrual cycle, which is also a common phenomenon.

Reply Date: 2023/05/12

More Info


When it comes to missed periods and the potential for pregnancy, there are several factors to consider. Based on your description, it appears that your period is delayed by 20 days, and you have not engaged in penetrative sexual intercourse, only manual stimulation. You also mentioned that you took a pregnancy test 18 days after your missed period, which returned a negative result.
Firstly, it's important to understand that a missed period can be caused by a variety of factors, including hormonal imbalances, stress, illness, changes in weight, and even certain medications. In your case, you mentioned having a throat infection and taking medication, which could potentially affect your menstrual cycle. Some medications can influence hormone levels, leading to changes in your cycle, including delays.

Regarding the pregnancy test, home pregnancy tests are generally quite reliable when used correctly. They work by detecting the hormone human chorionic gonadotropin (hCG), which is produced during pregnancy. A negative test result, especially when taken after a missed period, typically indicates that you are not pregnant. However, it is worth noting that if the test was taken too early or if there are any issues with the test itself, there is a small chance of a false negative. Given that you have not had penetrative intercourse, the likelihood of pregnancy is very low.

In terms of your health, if your period does not arrive soon, it would be advisable to consult with a healthcare provider. They can perform a more sensitive blood test for pregnancy and evaluate other potential causes for your missed period. Additionally, they can assess the impact of any medications you have taken and whether they might have contributed to your menstrual irregularities.

Stress is another significant factor that can affect your menstrual cycle. If you have been experiencing anxiety or stress, particularly related to your health or other life circumstances, this could also contribute to a delayed period. It’s essential to find ways to manage stress, as it can have a profound impact on your overall health and well-being.

In summary, based on the information provided, it seems unlikely that you are pregnant given the negative pregnancy test and the nature of your sexual activity. However, if your period does not return soon, or if you have any other concerning symptoms, it would be wise to seek medical advice. A healthcare professional can provide a thorough evaluation and help determine the underlying cause of your missed period, ensuring that you receive the appropriate care and guidance.

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