Post-Medication Bleeding and Fertility Concerns - Obstetrics and Gynecology

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Hello doctor, I went to see a gynecologist in November 2022 due to continuous bleeding.
The doctor said I only had endometrial thickening, so I was prescribed Dienogest for 6 months.
After my last follow-up on May 9th, I started to stop the medication.
During the treatment, I experienced intermittent bleeding, but after stopping the medication, I continued to bleed until May 13th.
Is this normal, or is it related to stopping the medication? Can I still get pregnant under these circumstances?

Shihan, 20~29 year old female. Ask Date: 2023/05/13

Dr. Lin Manying reply Obstetrics and Gynecology


Hello, Shihan: If you experience bleeding for more than a month after taking medication, it is recommended to return for a follow-up appointment.
Intermittent bleeding may indicate that ovulation has not yet occurred.
If you are trying to conceive, please consult your physician.
The Hualien Hospital of the Ministry of Health and Welfare cares about your health.

Reply Date: 2023/05/13

More Info


Understanding post-medication bleeding and fertility concerns can be quite complex, especially when dealing with hormonal treatments and their effects on the menstrual cycle. Based on your situation, it appears that you have been experiencing abnormal bleeding, which has been attributed to endometrial thickening. You were prescribed a medication (likely a progestin) to help manage this condition over a six-month period.
When you stop taking hormonal medications, it is not uncommon to experience some irregular bleeding or spotting as your body readjusts to its natural hormonal cycle. This phenomenon is often referred to as "withdrawal bleeding." The duration and intensity of this bleeding can vary significantly from person to person. In your case, since you stopped the medication on May 9 and continued to experience bleeding until May 13, this could be a normal response as your body transitions back to its natural hormonal state.
However, it is essential to monitor the bleeding. If it persists beyond a few days or becomes excessively heavy, it would be prudent to consult your healthcare provider. They may want to rule out other causes of bleeding, such as hormonal imbalances, structural issues within the uterus, or other underlying conditions.

Regarding your fertility concerns, the ability to conceive after stopping hormonal medications largely depends on how quickly your menstrual cycle returns to its normal rhythm. Many women find that their cycles normalize relatively quickly after discontinuing hormonal treatments, but for some, it may take a few cycles for ovulation to resume. If you are actively trying to conceive, it is advisable to track your menstrual cycle and ovulation signs.
If you continue to experience irregular bleeding or if your menstrual cycle does not normalize within a few months, it may indicate an underlying hormonal imbalance that could affect your fertility. In such cases, further evaluation by a healthcare provider is warranted. They may recommend blood tests to assess hormone levels, an ultrasound to evaluate the uterine lining, or other diagnostic procedures to ensure that there are no other issues affecting your reproductive health.

In summary, while some post-medication bleeding can be expected after stopping hormonal treatments, it is crucial to keep an eye on the duration and intensity of the bleeding. If you have concerns about your fertility or if the bleeding does not resolve, seeking further evaluation from a healthcare provider is essential. They can provide personalized guidance based on your specific health history and current situation. Remember, maintaining open communication with your healthcare provider is key to managing your reproductive health effectively.

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