Oral Medications for Toenail Fungus Treatment - Dermatology

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Oral medication for onychomycosis?


Hello! I have a fungal infection on my right big toe.
During my first visit to the hospital, after a blood test, the doctor prescribed an oral medication and instructed me to return in two weeks for another blood test.
However, when I got home, I found that the oral medication only had a supply for 3 days (Lamisil 250mg/tab), which is just 3 tablets.
Shouldn't I be taking it continuously every day? Since there are no outpatient services available during the holiday, I wanted to inquire about this here.
Thank you!

Miss Sun, 30~39 year old female. Ask Date: 2023/05/14

Dr. Wu Yuxin reply Dermatology


I'm not sure what the issue is with your prescription.
There are also pharmacists on duty at the pharmacy during the holidays, so you can call and ask them.

Reply Date: 2023/05/14

More Info


When it comes to treating toenail fungus, particularly with oral medications like Lamisil (Terbinafine), it's essential to understand the treatment protocol and the importance of adhering to the prescribed regimen.
First, let's clarify how oral antifungal medications work. Lamisil is an antifungal medication that is effective against dermatophytes, which are the fungi responsible for most nail infections. The drug works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, leading to cell death. This medication is typically prescribed for a duration that can range from several weeks to a few months, depending on the severity of the infection and the growth rate of the toenails.

In your case, it seems that you received a three-day supply of Lamisil, which is unusual for treating toenail fungus. Typically, the treatment involves taking the medication daily for a specified period, often 250 mg once daily for at least 6 to 12 weeks, depending on the nail's growth and the extent of the infection. The reason for this extended treatment is that toenails grow slowly, and it takes time for the medication to clear the infection completely and for the new, healthy nail to grow in.

If you have only received a three-day supply, it is crucial to follow up with your healthcare provider as soon as possible. You should clarify whether this was an oversight or if there is a specific reason for such a short course. It’s also important to ask about the follow-up blood tests that were mentioned. These tests are typically done to monitor liver function, as both Lamisil and other oral antifungals can affect liver enzymes.
Regarding your concern about not being able to see a doctor due to the holiday, you might consider contacting the clinic or pharmacy where you received the prescription. They may be able to provide guidance or an alternative solution, such as a refill or a temporary prescription until you can see your doctor.

Additionally, while you are waiting for your follow-up appointment, it’s advisable to maintain good foot hygiene. Keep your feet clean and dry, and avoid sharing footwear or nail clippers to prevent spreading the infection.
In summary, it is essential to take oral antifungal medications as prescribed and to complete the full course of treatment, even if symptoms improve before finishing the medication. Stopping the treatment prematurely can lead to a recurrence of the infection. Always communicate with your healthcare provider about any concerns or questions you have regarding your treatment plan. If you have further questions or need clarification, do not hesitate to reach out to your healthcare provider for assistance.

Similar Q&A

Alternative Treatments for Toenail Fungus Beyond Oral Medications

Oral terbinafine tablets are used to treat onychomycosis (fungal nail infection). After taking the medication for 28 days, if blood tests show elevated liver enzymes, the treatment should be discontinued. Are there other medications available for treatment?


Dr. Wu Yuxin reply Dermatology
Yes, you can discuss it with your physician.

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Hello: The treatment options for onychomycosis include topical antifungal medications or oral antifungal medications. However, oral antifungal medications should only be used in individuals with normal liver function. Response from Jiang Yujiao.

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Hello, could you please tell me what other effective oral medications are available for onychomycosis besides the oral medications that require six weeks for fingers and three months for toes? Additionally, besides Lamisil, are there any other effective topical treatments? What h...


Dr. Jiang Zheen reply Dermatology
The most commonly used oral medications for onychomycosis are two types: Lamisil (terbinafine) and Sporanox (itraconazole). Additionally, there is another medication called fluconazole, which is used less frequently due to its potentially greater side effects. As for topical medi...

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