Can You Use Scar Gel on Skin Discoloration After Monkeypox Vaccine? - Dermatology

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Skin pigmentation changes after receiving the monkeypox vaccine?


Hello Doctor, I received the monkeypox vaccine (intradermal injection) on April 25, and it was administered on my left forearm.
It has been four weeks since the vaccination, and the injection site no longer shows any redness, swelling, heat, or itching.
However, I have noticed some skin pigmentation at the site, which is slightly darker than the surrounding normal skin.
I happen to have some Mederma gel on hand, so I would like to ask if it is safe to apply Mederma gel on the pigmented area to help lighten the skin tone? Thank you.

Xiao An, 30~39 year old female. Ask Date: 2023/05/23

Dr. Wu Yuxin reply Dermatology


Beshuren gel is effective for scars, but it is not effective for simple hyperpigmentation.

Reply Date: 2023/05/23

More Info


After receiving the monkeypox vaccine, it is not uncommon for some individuals to experience skin discoloration at the injection site. This discoloration can manifest as hyperpigmentation, where the affected area appears darker than the surrounding skin. This phenomenon is typically a result of the skin's natural healing process and can occur due to various factors, including inflammation, trauma, or even the injection itself.

Regarding your question about using scar gel, such as the one you mentioned (倍舒痕凝膠), it is generally safe to apply topical treatments designed for scar reduction on areas of hyperpigmentation, provided that the skin is intact and free from any open wounds or active irritation. Scar gels often contain ingredients that can help in the healing process and may assist in reducing the appearance of discoloration over time. Common ingredients in these gels include silicone, which helps to hydrate the skin and improve its texture, as well as other compounds that may promote skin regeneration.

However, it is essential to consider a few factors before proceeding:
1. Skin Sensitivity: Ensure that your skin is not overly sensitive or reactive. If you have a history of skin reactions to topical products, it may be wise to perform a patch test on a small area before applying the gel to the entire affected area.

2. Timing: Since it has been four weeks since your vaccination, the initial inflammatory response should have subsided. However, if you notice any signs of irritation or if the discoloration worsens after applying the gel, discontinue use and consult a healthcare professional.

3. Consultation with a Dermatologist: If you are uncertain about the appropriateness of using the gel or if the discoloration persists, it is advisable to consult a dermatologist. They can provide tailored advice based on your skin type and the specific characteristics of the discoloration.

4. Additional Treatments: Depending on the severity of the hyperpigmentation, a dermatologist may recommend additional treatments, such as topical agents containing hydroquinone, retinoids, or chemical peels, which can be more effective in addressing pigmentation issues.

5. Sun Protection: It is crucial to protect the affected area from sun exposure, as UV rays can exacerbate hyperpigmentation. Using a broad-spectrum sunscreen with a high SPF can help prevent further darkening of the area.

In conclusion, while it is generally safe to use scar gel on the area of skin discoloration following your monkeypox vaccination, it is essential to monitor your skin's response and consult with a healthcare professional if you have any concerns. The healing process can take time, and patience is key when addressing skin discoloration.

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