Unexplained Joint Pain: Chronic Bone Discomfort - Orthopedics

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Pain in various joints throughout the body for unknown reasons?


I have been experiencing bone pain for about ten years, but my family told me it was growing pains.
Even after turning 18, I still frequently have unexplained bone pain in my wrists, elbows, ankles, knees, calves, and thighs—essentially, all my limbs hurt.
I also experience generalized bone itching, which makes me want to move my joints.
About three years ago, I consulted a neurologist and underwent a neurological examination of my limbs, but the doctor said my nervous system was normal, and my EEG was also normal.
I mentioned my bone pain, which sometimes gets so severe that I can't sleep or even feel like crying, but the doctor said the reports did not indicate any issues.
Occasionally, I also experience significant numbness in my legs, which makes them feel weak and very uncomfortable.
I have been seeing a traditional Chinese medicine practitioner for stomach issues, and the doctor suggested that poor blood circulation might be causing oxygen deficiency.

I still find the bone itching and pain very troubling, especially since it has persisted for so long.
At the end of last year, I visited a rheumatologist and had an ultrasound of my right wrist.
The doctor indicated that my joints were chronically inflamed.
I also underwent genetic testing and immune system assessments; the genetic tests showed no issues, but the immune system tests indicated potential problems, suggesting I am on the verge of developing a condition, requiring follow-up every two years.
I had a comprehensive health check-up last year, which did not reveal any significant problems.
Even after blood tests (including cancer screenings), the causes of my bone itching and pain remain unclear.
Just yesterday, I suddenly experienced pain from my knees to the upper thighs, which improved after a shower but became very painful again before bed, and I felt fine upon waking up.
I hope to receive answers soon.
Thank you to the doctor for your patient examination.

huàn xióng, 20~29 year old female. Ask Date: 2023/05/31

Dr. You Dianqi reply Orthopedics


Hello, it is recommended to visit an orthopedic clinic for evaluation.
Thank you.

Reply Date: 2023/05/31

More Info


Unexplained joint pain, especially when it has persisted for many years, can be quite challenging both physically and emotionally. Your experience of chronic bone discomfort, along with the accompanying symptoms of itching and numbness, suggests that there may be underlying issues that have yet to be fully diagnosed or understood.

From your description, it seems that you have undergone a thorough evaluation, including neurological assessments, imaging studies, and consultations with specialists in rheumatology and immunology. The fact that your neurological examinations returned normal results is reassuring, as it suggests that there is no significant nerve damage or neurological disorder contributing to your symptoms. However, the persistent joint pain and inflammation you mentioned, particularly in your wrists, elbows, ankles, knees, and legs, warrant further investigation.

Chronic joint pain can arise from various conditions, including but not limited to:
1. Inflammatory Arthritis: Conditions such as rheumatoid arthritis or psoriatic arthritis can cause joint pain and inflammation. These conditions often require specific blood tests and imaging studies to diagnose.

2. Osteoarthritis: This degenerative joint disease can lead to pain and stiffness, particularly as one ages. It is characterized by the breakdown of cartilage in the joints.

3. Fibromyalgia: This condition is characterized by widespread musculoskeletal pain, fatigue, and tenderness in localized areas. It can also cause sleep disturbances and emotional distress.

4. Vascular Issues: As your traditional Chinese medicine practitioner suggested, poor blood circulation can lead to symptoms of pain and numbness. Conditions like peripheral artery disease could be a factor.

5. Autoimmune Disorders: Since your immune system tests indicated some abnormalities, it might be worth exploring autoimmune conditions further. These can sometimes present with joint pain and systemic symptoms without clear diagnostic markers.

6. Chronic Fatigue Syndrome: This condition can also manifest with joint pain, fatigue, and sleep disturbances, and it often overlaps with fibromyalgia.

Given your symptoms of joint pain, itching, and numbness, it may be beneficial to consider the following steps:
- Follow-Up with a Rheumatologist: Since you have already seen a rheumatologist, it may be worthwhile to return for a follow-up, especially if your symptoms have worsened or changed. Discuss the possibility of further testing, such as more specific autoimmune panels or imaging studies.

- Physical Therapy: Engaging in physical therapy may help improve joint function and reduce pain. A physical therapist can tailor a program to your specific needs, focusing on strengthening and flexibility exercises.

- Lifestyle Modifications: Consider dietary changes that may reduce inflammation, such as incorporating omega-3 fatty acids, antioxidants, and avoiding processed foods. Regular exercise, even low-impact activities like swimming or walking, can also be beneficial.

- Pain Management: Discuss pain management strategies with your healthcare provider. This could include medications, topical treatments, or alternative therapies like acupuncture.

- Monitoring Symptoms: Keep a detailed diary of your symptoms, noting when they occur, their intensity, and any potential triggers. This information can be invaluable for your healthcare provider in determining the next steps.

In conclusion, while the journey to understanding chronic joint pain can be frustrating, it is essential to continue advocating for your health. Collaborate closely with your healthcare team, and do not hesitate to seek second opinions if necessary. Your symptoms deserve thorough investigation, and with persistence, you may find the answers and relief you seek.

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