Can You Get the HPV Vaccine Again After 13 Years? - Urology

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Can the HPV vaccine be administered multiple times?


Hello, doctor: I received the HPV vaccine (3 doses) in 2010, and now it's 2023.
After 13 years, do I need to get re-vaccinated for HPV? If re-vaccination is possible, I am already 46 years old, and I'm unsure if it's appropriate for me to receive the vaccine since the information states it's recommended up to age 45.
Thank you.

Xiao Ai, 40~49 year old female. Ask Date: 2023/06/01

Dr. Chen Jiansheng reply Urology


Please seek medical attention.

Reply Date: 2023/06/01

More Info


The question of whether a 46-year-old woman who received the HPV vaccine series in 2010 should get vaccinated again in 2023 is a nuanced one. The HPV vaccine, particularly the Gardasil 9, is designed to protect against several strains of the human papillomavirus (HPV) that are known to cause cervical cancer and genital warts. The vaccine is most effective when administered before the onset of sexual activity, which is why it is typically recommended for preteens and young adults.

As of the latest guidelines, the HPV vaccine is generally recommended for individuals up to the age of 26. However, individuals aged 27 to 45 may also benefit from vaccination based on shared clinical decision-making. This means that if you are in this age range and have not been previously vaccinated or are unsure of your HPV status, discussing the option of revaccination with your healthcare provider could be beneficial.

In your case, since you completed the full vaccination series of three doses in 2010, you should have adequate protection against the HPV strains covered by the vaccine. Research indicates that the immunity provided by the HPV vaccine is long-lasting, and there is no current recommendation for booster doses for those who have completed the series. Therefore, it is generally not necessary to receive the HPV vaccine again after 13 years if you have already completed the series.

However, if you have concerns about your HPV status or if you have had new sexual partners since your last vaccination, it may be worth discussing with your healthcare provider. They can assess your individual risk factors and determine whether additional vaccination or screening (such as Pap smears or HPV testing) is appropriate.

Regarding your age, while the vaccine is typically recommended for those under 45, it is not contraindicated for those over this age limit. The decision to vaccinate should be made in consultation with a healthcare professional who can evaluate your specific health history and risk factors.

In summary, while it is unlikely that you need to receive the HPV vaccine again after 13 years, it is essential to have a conversation with your healthcare provider to ensure that you are adequately protected and to discuss any potential need for further vaccination or screening based on your individual circumstances.

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