Oral Lichen Planus: Concerns About Biopsy and Healing - Dentistry

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Oral lichen planus, oral mucosal ulcers, tongue ulcers?


Hello Doctor: I was recently diagnosed with possible oral lichen planus, with reticular and ulcerative forms.
The doctor recommended a biopsy for further confirmation, but I am concerned that the biopsy site may heal poorly or worsen the ulcers.
Since I started treatment three months ago, I have been applying an oral ointment, and during this time, the ulcers on my oral mucosa have improved.
However, in the last two months, I developed ulcers on the underside of my tongue.
I have been using the oral ointment for two weeks without improvement, so I returned for a follow-up.
The doctor prescribed an oral ointment along with B vitamins and zinc.
After three weeks of using the ointment and taking the supplements, the ulcer on my tongue has not healed.
I have now started taking steroids and colchicine for a week, and the tongue ulcer seems to be slightly less red and painful, but it is still not completely healed.
Do I really need to undergo a biopsy? I am very worried about the healing of the biopsy site.
Thank you for your response, Doctor.

yi, 30~39 year old female. Ask Date: 2023/06/04

Dr. Zeng Guanghui reply Dentistry


Oral lichen planus is recommended for biopsy because some studies suggest it may be a warning sign of oral cancer.
Additionally, if a tongue ulcer does not improve after two weeks, it is advisable to consult an oral surgeon or an otolaryngologist to evaluate the need for a biopsy.
Dr.
Tseng Guang-Hui, Department of Dentistry, Nantou Hospital.

Reply Date: 2023/06/04

More Info


Oral lichen planus (OLP) is a chronic inflammatory condition that affects the mucous membranes inside the mouth. It can manifest in various forms, including reticular (net-like) and erosive (ulcerative) types. The erosive form, which you seem to be experiencing, can lead to painful ulcers that significantly impact quality of life. Your concerns about undergoing a biopsy are valid, especially considering the potential for further irritation or complications in an already sensitive area.


Understanding the Need for a Biopsy
A biopsy is often recommended to confirm the diagnosis of oral lichen planus and to rule out other conditions that may mimic its symptoms, such as oral cancer or other autoimmune diseases. While it is understandable to worry about the healing process post-biopsy, it is important to note that the benefits of obtaining a definitive diagnosis often outweigh the risks. A biopsy can provide crucial information that can guide your treatment plan, especially if the lesions are not responding to standard therapies.


Healing Process and Management
The healing of a biopsy site can vary from person to person, and while there is a risk of delayed healing or exacerbation of existing ulcers, most patients do heal without significant complications. After a biopsy, it is essential to follow your healthcare provider's post-procedure care instructions, which may include:
1. Avoiding Irritants: Steer clear of spicy, acidic, or abrasive foods that could irritate the biopsy site.

2. Maintaining Oral Hygiene: Continue to practice good oral hygiene, but be gentle around the biopsy area. Use a soft-bristled toothbrush and consider using a mild mouthwash.

3. Pain Management: Over-the-counter pain relief medications may be recommended to manage discomfort.

4. Follow-Up Care: Regular follow-ups with your healthcare provider are crucial to monitor healing and adjust treatment as necessary.


Current Treatment Considerations
You mentioned that you have been using topical corticosteroids and other medications without complete resolution of your symptoms. This suggests that your condition may require a more tailored approach. Here are some considerations:
- Corticosteroids: These are often the first line of treatment for OLP, particularly for the erosive type. If your current regimen is not effective, your doctor may consider adjusting the dosage or switching to a different formulation.

- Immunosuppressants: In cases where corticosteroids are insufficient, other immunosuppressive agents may be considered.

- Nutritional Support: Since you are taking B vitamins and zinc, ensure that you are getting adequate nutrition, as deficiencies can exacerbate mucosal conditions.

- Regular Monitoring: Given the chronic nature of OLP, regular monitoring by a specialist is essential to manage flare-ups and adjust treatment as needed.


Conclusion
In summary, while the thought of undergoing a biopsy can be daunting, it is a necessary step in confirming the diagnosis of oral lichen planus and ensuring that you receive the most appropriate treatment. The potential for complications exists, but with proper care and management, most patients heal well. It is crucial to maintain open communication with your healthcare provider about your concerns and treatment progress. If you feel uncertain about the biopsy, discussing your fears and the potential benefits with your doctor can help you make an informed decision. Remember, managing a chronic condition like OLP often requires a multifaceted approach, and your proactive involvement in your care is vital for achieving the best outcomes.

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